International Science Community Association Research Journal of Chemical Sciences 2231 - 606X 7 8 2017 08 18 Synthesis and characterization of 2-[(hydroxy(4-nitrophenyl) methyl] cyclohexanone for its potential application as off-on fluorescent sensor for selective cadmium detection 7 18 EN Piyush Kant Pandey 1 Bhilai Institute of Technology Raipur, Kendri, NH-43, New Raipur-493661, Chhattisgarh, India Rekha Trivedi 2 Department of Chemistry, Shri shankaracharya Technical Campus, Bhilai-490020 Chhattisgarh, India Madhurima Pandey 3 Department of Chemistry, Bhilai Institute of Technology, Durg-491001, Chhattisgarh, India Maria Sadia 1 Department of Chemistry, University of Malakand, Chakdara, Lower Dir, Khyber Pakhtunkhwa, Pakistan Muhammad Naveed Umar 2 Department of Chemistry, University of Malakand, Chakdara, Lower Dir, Khyber Pakhtunkhwa, Pakistan Robina Naz 3 Department of Chemistry, University of Malakand, Chakdara, Lower Dir, Khyber Pakhtunkhwa, Pakistan Jahangir Khan 4 Department of Chemistry, University of Malakand, Chakdara, Lower Dir, Khyber Pakhtunkhwa, Pakistan Rizwan Khan 5 Department of Chemistry, University of Malakand, Chakdara, Lower Dir, Khyber Pakhtunkhwa, Pakistan > Research Paper 2017 4 25 2017 08 18 2-[hydroxy(4-nitrophenyl)methyl]cyclohexanone (R) has been synthesized, purified (column chromatography) and characterized by 1H NMR. The fluorescence properties of chemosensor (R) were studied in acetonitrile for the sensing of alkali, alkaline and transition metal ions (Mg2+, Cd2+, Ni2+, Zn2+, Ba2+, Co2+, Cu2+, Pb2+, Na1+). Interaction of Cd2+ with chemosensor R displayed a significant fluorescence enhancement as compared to other examined cations. Maximum emission was observed at pH 10. According to job’s plot analysis binding ratio of the complex R-Cd2+ was found to be 1:1. No significant interference was observed in the presence of competitive metal ions. The fluorescence of chemosensor R exhibits a good linear fluorescent response towards Cd2+ in the range 1-140 µM. The chemosensor R showed good binding constant to Cd2+ calculated as 1×106 M-1 using Benesi-Hilderbrand equation. The synthesized fluorescent chemosensor R was used successfully to determine Cd2+ in aqueous solution with a detection limit in µ range. Copyright@ International Science Community Association