International Science Community Association Research Journal of Chemical Sciences 2231 - 606X 7 3 2017 03 18 Polyaniline-CdS nanocomposite/GOx matrix modified optical fiber based biosensor for glucose detection 33 35 EN H. Devnani 1 Department of Chemistry, Dayalbagh Educational Institute, Agra - 282005, India S. Ansari 2 Department of Chemistry, Dayalbagh Educational Institute, Agra - 282005, India S.P. Satsangee 3 Department of Chemistry, Dayalbagh Educational Institute, Agra - 282005, India Meher Jagamohan 1 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Mazumdar Bidyut 2 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Dixit Neena 3 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Keshav Seema 4 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Keshav Amit 5 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Savant Mahesh M. 1 Department of Industrial Chemistry, Shree M. & N. Virani Science College, Kalawad Road, Rajkot, India Patel Ramesh N. 2 Department of Chemistry, Municipal Arts & Urban Science College, Mahesana, Gujarat, India Khistariya Anand V. 3 Department of Industrial Chemistry, Shree M. & N. Virani Science College, Kalawad Road, Rajkot, India S.C. Biswas 1 Rain Forest Research Institute, P.B. 136, Sotai Ali, Jorhat, Assam-785001, India P. Hazarika 2 Rain Forest Research Institute, P.B. 136, Sotai Ali, Jorhat, Assam-785001, India N.B. Dutta 3 Rain Forest Research Institute, P.B. 136, Sotai Ali, Jorhat, Assam-785001, India Sarmah H. 4 Rain Forest Research Institute, P.B. 136, Sotai Ali, Jorhat, Assam-785001, India Dagdale S.R. 1 Department of Physics S. G. B. Amravati University, Amravati, MS - 444 602, India Harde G.B. 2 Department of Physics S. G. B. Amravati University, Amravati, MS - 444 602, India and Department of Physics, Shri Ramnath Ramgopal Lahoti Science College, Morshi, MS - 444905, India Pahurkar V.G. 3 Department of Physics S. G. B. Amravati University, Amravati, MS - 444 602, India Muley G.G. 4 Department of Physics S. G. B. Amravati University, Amravati, MS - 444 602, India Pahurkar V.G. 1 Department of Physics, Sant Gadge Baba Amravati University, Amravati (MS), India-444602 Nagale V.K. 2 Department of Zoology, Sant Gadge Baba Amravati University, Amravati (MS), India-444602 Gambhire A.B. 3 Department of Chemistry, Shri Anand College of Science, Pathardi, Ahmednagar (MS), India-414102 Muley G.G. 4 Department of Physics, Sant Gadge Baba Amravati University, Amravati (MS), India-444602 > Short Communication 2016 3 22 2017 03 18 In the present study, polyaniline-cadmium sulphide (PANI-CdS) nanocomposite material was synthesized by simple chemical polymerization method using FeCl3 as an oxidant. The prepared matrix was deposited as an active cladding material for the fabrication of cladding modified fiber optic intrinsic biosensor. The cladding modified material was used for the immobilization of biomolecules-enzyme-glucose oxidase (GOx) with the help of cross-linking technique. The nature of deposited nanocomposite material was confirmed using X-ray diffraction (XRD) analysis and field emission scanning electron microscopy (FE-SEM) techniques. Moreover, optical microscopy was used to observe the thin layer of deposited nanocomposite matrix on fiber optic sensing element. The prepared sensor can be used further for the detection of glucose solution of various concentrations. From the results, it has been found that PANI-CdS nanocomposite is biocompatible for the fixation of biomolecules on fiber optic sensing element. The results have been presented. Copyright@ International Science Community Association