International Science Community Association Research Journal of Chemical Sciences 2231 - 606X 7 3 2017 03 18 Synthesis of carboxamide and sulfonamide bearing novel pyrazolopyridones 19 22 EN H. Devnani 1 Department of Chemistry, Dayalbagh Educational Institute, Agra - 282005, India S. Ansari 2 Department of Chemistry, Dayalbagh Educational Institute, Agra - 282005, India S.P. Satsangee 3 Department of Chemistry, Dayalbagh Educational Institute, Agra - 282005, India Meher Jagamohan 1 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Mazumdar Bidyut 2 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Dixit Neena 3 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Keshav Seema 4 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Keshav Amit 5 Department of Chemical Engineering, National Institute of Technology, Raipur-492010, Chhattisgarh, India Savant Mahesh M. 1 Department of Industrial Chemistry, Shree M. & N. Virani Science College, Kalawad Road, Rajkot, India Patel Ramesh N. 2 Department of Chemistry, Municipal Arts & Urban Science College, Mahesana, Gujarat, India Khistariya Anand V. 3 Department of Industrial Chemistry, Shree M. & N. Virani Science College, Kalawad Road, Rajkot, India > Research Paper 2016 11 25 2017 03 18 The reaction of pyridones with hydrazine hydrate to furnished pyrazolopyridones 1a-l followed by reaction with p-Toluenesulfonyl chloride in basic condition affords 2a-l in high yields with short reaction time. The pyridone derivatives were prepared by the reaction of ketene dithioacetals (KDTA) with cyanoacetamide usingsodium isopropoxide as an effective base. The reactions were carried out with range of solvent and found i-Propyl alcohol as suitable solvent. We have demonstrated the process of highly functionalized pyrazolopyridones in high yields. Copyright@ International Science Community Association