International Science Community Association Research Journal of Chemical Sciences 2231-606X 12 1 2022 02 18 Efficacy of a combination of antiseptics over a single agent for microbial control in a household setting 64 66 EN I.A. Ajayi 1 Industrial Unit, Chemistry Department, Faculty of Science, University of Ibadan, Nigeria O.B. Omolere 2 Industrial Unit, Chemistry Department, Faculty of Science, University of Ibadan, Nigeria Pachouri Manoj Kumar 1 Applied Science Department, Anand Engineering College, Keetham, Agra, 282007, India Mittal Pankaj 2 Applied Science Department, Anand Engineering College, Keetham, Agra, 282007, India Upadhyay Monika 1 Department of chemistry, University of Rajasthan, Jaipur 302004, India Singh R.V. 2 Department of chemistry, University of Rajasthan, Jaipur 302004, India Fahmi Nighat 3 Department of chemistry, University of Rajasthan, Jaipur 302004, India Sharma Asmita 1 Dept. of Chemistry, Shri Vaishnav Vidyapeeth Vishwavidyalaya, Indore, MP, India Sharma Rajesh 2 Devi Ahilya Vishwavidyalaya, Takshshila Campus, Khandwa Road, Indore, MP, India Mohammed Aliyu D. 1 Department of Chemistry, Umaru Musa Yar’adua University, PMB 2218, Katsina, Katsina state, Nigeria Abubakar Maryam Dodo 2 Department of Chemistry, Umaru Musa Yar’adua University, PMB 2218, Katsina, Katsina state, Nigeria Rathore Monika 1 Analytical Laboratory, Chemistry Department, Jai Narain Vyas University, Jodhpur, Rajasthan, India Singh Ishwar 2 Analytical Laboratory, Chemistry Department, Jai Narain Vyas University, Jodhpur, Rajasthan, India Bhati Punam Singh 3 Analytical Laboratory, Chemistry Department, Jai Narain Vyas University, Jodhpur, Rajasthan, India Nagar Sarika 4 Analytical Laboratory, Chemistry Department, Jai Narain Vyas University, Jodhpur, Rajasthan, India A.A. Siaka 1 Department of Applied Chemistry Federal University Dutsin-Ma Katsina State, Nigeria A. Ismail 2 Department of Applied Chemistry Federal University Dutsin-Ma Katsina State, Nigeria Somashekar Manjunatha A. 1 Department of Chemistry, Don Bosco Institute of Technology (Affiliated to Visvesvaraya Technological University - Belagavi), Mysore Road, Bengaluru 560 074, India Sukhdev Anu 2 Department of Chemistry, Presidency University, Bengaluru-560 064, India . Puttaswamy 3 Department of Chemistry, Jnanabharati Campus, Bangalore University, Bangalore-560 056, India T.S. Shashidhara 4 Department of Physics, Siddaganga College of Arts, Science and Commerce, Tumakuru, 572102, India Ahmed Abubakar Abdullahi 1 Department of Pure and Applied Chemistry, Faculty of Science, University of Maiduguri, P.M.B. 1069, Maiduguri, Borno State, Nigeria Chindo Almustapha Sulaiman 2 Department of Pure and Applied Chemistry, Faculty of Science, University of Maiduguri, P.M.B. 1069, Maiduguri, Borno State, Nigeria Mohammed Abdullahi Idi 3 Department of Pure and Applied Chemistry, Faculty of Science, University of Maiduguri, P.M.B. 1069, Maiduguri, Borno State, Nigeria Joshi Shashank S. 1 Computer Science, VIT Pune. 7- Professor VIT Pune, India Joshi Shital S. 2 Consultant Pathologist Sahyadri Speciality Labs, Pune, India > Short Communication 2021 4 14 2022 02 18 Antiseptics and disinfectants are extensively used in hospitals and Health care settings as well as homes for a variety of hard surface cleaning applications. Each group of antiseptics and disinfectants has their advantages and disadvantages. Efficacy and safety are major concerns in choosing disinfectants. Unlike antibiotics, Disinfectants are rarely tested for their efficacy. We tested a combination of Disinfectants Cetrimide, Formaldehyde and Benzlkonium chloride against single agent cetrimide. We found that “Combicide One” our combination proved much superior to the single agent. A combination of disinfectants is very important to enhance efficacy of these disinfectants towards the controlling microbial population which will lead to prevention of disease transmission and infection. Copyright@ International Science Community Association