International Science Community Association Research Journal of Chemical Sciences 2231-606X 11 1 2021 02 18 Anti-covid repurposed drug Remedesivir: Zhangs catalytic chiral approach 84 86 EN Sandala Anuradhabai 1 S.N.Vanita Pharmacy Mahavidyalaya, Tarnaka, Hyderabad-500007, Telangana, India Yasaswi P. Soma 2 S.N.Vanita Pharmacy Mahavidyalaya, Tarnaka, Hyderabad-500007, Telangana, India Ravindernath A. 3 Faculty of Pharmacy, Osmania University, Hyderabad- 500007 Telangana, India Patnaik K.S.K. Rao 4 Department of Chemical Engineering, Dire Dawa Institute of Technology, P.box.1362, Dire Dawa University, Ethiopia Elnaeim Omar E.B. 1 Department of Chemistry and Biology, Faculty of Education University of Al-Butana, Rufaa, Sudan Ragab Yousif Ali 2 Department of Chemical Engineering and Chemical Technology, Faculty of Engineering and Technology, University of Gezira, Medani, Sudan Vanjeri Vinayak N. 1 P G Department of Studies in Chemistry, Karnatak University, Dharwad - 580 003, India Goudar Naganagouda 2 P G Department of Studies in Chemistry, Karnatak University, Dharwad - 580 003, India Hiremani Vishram 3 P G Department of Studies in Chemistry, Karnatak University, Dharwad - 580 003, India Gasti Tilak 4 P G Department of Studies in Chemistry, Karnatak University, Dharwad - 580 003, India Sataraddi Sarala P. 5 P G Department of Studies in Chemistry, Karnatak University, Dharwad - 580 003, India Masti Saraswati P. 6 Department of Chemistry, Karnatak Science College, Dharwad - 580 001, India Chougale Ravindra B. 7 P G Department of Studies in Chemistry, Karnatak University, Dharwad - 580 003, India Onuorah Nnamani Johnson 1 Department of Chemistry, Benue State University, Makurdi, Benue State, Nigeria Agbidye I.G 2 Department of Chemistry, Benue State University, Makurdi, Benue State, Nigeria Dominique CHODATON-ZINSOU Marthe 1 Laboratoire de pharmacognosie et des huiles essentielles, Faculte des Sciences et Techniques, Universite d’Abomey-Calavi, BENIN Arnaud ASSOGBA 2 Laboratoire de surveillance environnemental de la Direction Generale de l’Environnementet du Climat du Ministère de Cadre de Vie et du Developpement Durable, BENIN Jacques KOUAZOUNDE 3 Laboratoire de Chimie inorganique et Environnement (LaCIE), Faculte des Sciences et Techniques, Universite d’Abomey-Calavi, BENIN Fidèle ASSOGBA M. 4 Laboratoire de pharmacognosie et des huiles essentielles, Faculte des Sciences et Techniques, Universite d’Abomey-Calavi, BENIN Fernand GBAGUIDI 5 Laboratoire de pharmacognosie et des huiles essentielles, Faculte des Sciences et Techniques, Universite d’Abomey-Calavi, BENIN Joachim GBENOU 6 Laboratoire de pharmacognosie et des huiles essentielles, Faculte des Sciences et Techniques, Universite d’Abomey-Calavi, BENIN Daouda MAMA 7 Laboratoire d’Hydrologie Appliquee, Institut National de l’Eau, Universite d’Abomey-Calavi, BENIN Sarma Biswajit 1 Department of Chemistry, Royal School of Applied and Pure Sciences, Royal Global University, Guwahati-781035, Assam, India Jadhav P.M. 1 Department of Chemistry, Shri Muktanand College, Gangapur, Aurangabad, MS, India Prajapati Neha I. 1 Department of Chemistry, C.B. Patel Computer College & J.N.M. Patel Science College, Surat, India Vashi Rajendra T. 2 Chemistry Department, Navyug Science College, Surat-395009, India Hegde R.N. 1 Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire-574 240, India Vishwanatha P. 2 Department of Chemistry, Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire-574 240, India Nandibewoor S.T. 3 P.G. Department of Studies in Chemistry, Karnatak University, Dharwad-580 003, India Varala Ravi 1 Scrips Pharma, Mallapur, Hyderabad, Telangana-500 076, India > Short Review Paper 2020 12 23 2021 02 18 Herein, author has given glimpses of possible treatment agents for the SARS-COV2 infections and discussed the case study of the synthetic utility of Remedesivir in the present scenario by highlighting Zhangs catalytic asymmetric synthetic approach. It is shown that the chiral bicyclic imidazole catalyst plays vital role for the better stereoselectivity with excellent reactivity via dynamic kinetic asymmetric transformation (DyKAT). Copyright@ International Science Community Association