International Science Community Association International Research Journal of Biological Sciences 2278-3202 9 3 2020 08 10 Histological study, phytochemical screening and TLC studies of Sesbania grandiflora 43 47 EN R Akaniro Ifunanya 1 Department of Microbiology, University of Nigeria, Nsukka, Enugu State, Nigeria H Anumudu Obinna 2 Department of Microbiology, University of Nigeria, Nsukka, Enugu State, Nigeria N Ofonegbu Mercy 3 Department of Microbiology, University of Nigeria, Nsukka, Enugu State, Nigeria P Nebo Aisha 4 Department of Microbiology, University of Nigeria, Nsukka, Enugu State, Nigeria Mondal Astom 1 Department of Botany, University of Kalyani, Kalyani-741235, West Bengal, India Sinha Sankar Narayan 2 Department of Botany, University of Kalyani, Kalyani-741235, West Bengal, India Nnenna Omorodion 1 Department of Microbiology University of Port Harcourt P.M.B 5323 Port Harcourt Rivers State, Nigeria ijuo Philomena 2 Department of Microbiology University of Port Harcourt P.M.B 5323 Port Harcourt Rivers State, Nigeria P.V. Divya 1 Dept. in Microbiology, Manonmaniam Sundaranar University, Tirunelveli Rd, Abishekapatti, Tamil Nadu K. Sukesh 2 Dept. in Microbiology, Malankara Catholic College, Mariagiri, Tamil Nadu, India T. Ashitha 1 Research and Development Centre, Bharathiar University, Coimbatore-641 046, Tamil Nadu, India K. Seedikkoya 2 M.E.S. Mampad College, Malappuram District-676 542, Kerala, India J.O. Arogbodo 1 Department of Animal Production and Health, Federal University of Technology, Akure, Ondo State, Nigeria I.A. Adebayo 2 Department of Animal Production and Health, Federal University of Technology, Akure, Ondo State, Nigeria J.A. Adesida 3 Department of Animal Production and Health, Federal University of Technology, Akure, Ondo State, Nigeria Abdallah Lubna 1 Department of Biology & Biotechnology, Faculty of Science, An-Najah National University, Nablus, P.O. Box 7, Palestine Omar Ghadeer 2 Department of Biology & Biotechnology, Faculty of Science, An-Najah National University, Nablus, P.O. Box 7, Palestine Arora Sumit K. 1 Pharmacognosy and Phytochemistry Department, Gurunanak College of Pharmacy, Nari, Nagpur- 440 026, Maharashtra, India Itankar Prakash R. 2 University Department of Pharmaceutical Sciences, Department of Pharmacognosy and Phytochemistry, Rashtrasant Tukadoji Maharaj Nagpur University, Amravati Road, Nagpur- 440 033, Maharashtra, India Yende Subhash R. 3 Pharmacology Department, Gurunanak College of Pharmacy, Nari, Nagpur- 440 026, Maharashtra, India > Short Communication 2020 3 26 2020 08 10 Sesbania grandiflora (S. grandiflora), folklore medicinal plant is used in various parts of world. Leaves were used as alexeteric, for epilepsy, nyctalopia, gout, anthelmintic, itch, leprosy and ophthalmia. The plant possesses various therapeutic properties such as antiphlogistic, mildly laxative, anthelmintic, odontalgic properties and antirheumatic. The flowers were used as aperitif and refrigerant, for bronchitis, biliousness (abhorrence), gout, nyctalopia (night blindness), ozoena and quartan fever. Roots and barks were used in inflammation and as astringent respectively. In the present investigation phytochemical screening, histological examination and thin layer chromatographic identification of bark and extracts has been studied extensively and provided diagnostic key to spot adulterant. It is concluded that our research data helps to isolate and characterize the different phytochemicals responsible for medicinal potential of the S. grandiflora as anticancer, antiinflammatory, antibacterial, anxiolytic and anticonvulsant. Copyright@ International Science Community Association