International Science Community Association International Research Journal of Biological Sciences 2278-3202 8 5 2019 05 10 A review on effect of different plant extract against multidrug resistant bacteria 29 32 EN Mishra S. 1 Department of Biomedical Science, Shaheed Rajguru College of Applied Sciences for Women, University of Delhi, Delhi-110096, India Khatri M. 2 Department of Biomedical Science, Shaheed Rajguru College of Applied Sciences for Women, University of Delhi, Delhi-110096, India Mehra V. 3 Department of Biomedical Science, Shaheed Rajguru College of Applied Sciences for Women, University of Delhi, Delhi-110096, India Mohd. Yousuf Paray* and Parminder Singh Dehar 1 Department of Zoology and Environmental Science, Punjabi University, Patiala-147002, India Dilip B. Meshram 1 Department of Zoology, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur-440033, India Suresh C. Masram 2 Department of Zoology, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur-440033, India Vidya V. Baile 3 Department of Zoology, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur-440033, India Sameer Ahmad Thoker 1 School of Studies in Botany, Jiwaji University, Gwalior, MP, India Sapan Patel 2 School of Studies in Botany, Jiwaji University, Gwalior, MP, India Akshatha S.J. 1 Department of Microbiology, KLE Society's Institute of Dental Sciences, Bangalore, India > Review Paper 2019 2 15 2019 05 10 Multidrug resistance in bacteria is current problems for which many researches are being conducted to find a solution. There are different resistance mechanisms which the bacteria's have been adopting like mutation, by passing the target, efflux pumps etc. Herbal medicine has now drawn attention of world. Use of plant extracts against the bacterial could possibly reduce the antibiotic resistant which is mostly prevailing at present. Aloe Vera, Ginger, Garlic etc. have shown significant antibacterial activity against the multidrug resistant bacteria. In most of the studies Disk diffusion method was seen as the most commonly used method in finding the susceptibility of the extracts followed by determining the extracts Minimum inhibitory concentration. This is a review on resistance mechanism adopted by bacteria, and plant extract which have shown significant activity against the gram negative and gram positive bacteria. Copyright@ International Science Community Association