International Science Community Association International Research Journal of Biological Sciences 2278-3202 8 3 2019 03 10 Antimicrobial activity of bioactive molecules isolated from filamentous fungi 13 18 EN Noura E. Abd El-Hameed 1 Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt Haiam A. Mohammed 2 Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt El-Badry A.A. 3 Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt Hamada M.M.Z. 4 Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt Esmail Noghanchi 1 Department of Biology, Faculty of Science, University of Guilan, Rasht, Iran Hossein Javanbakht 2 Department of Biology, Faculty of Science, University of Guilan, Rasht, Iran Meghna Shrivastava 1 Faculty of Biological and Chemical Sciences, MATS University, Raipur, (C.G), India Ashish Saraf 2 MATS School of Biological and Chemical Sciences, MATS University, Raipur (C.G), India > Research Paper 2018 11 12 2019 03 10 Various microorganisms display antagonism as a principle phenomenon for the production of secondary metabolites. The present study aims at employing this antagonistic property of fungi for the production of some useful bioactive secondary metabolites. 53 isolates were screened for the production of antimicrobials after the incorporation of lactose which triggered the production of secondary metabolites, out of which only 3 showed positive results against the test pathogens. These were identified as Aspergillus flavus var flavus, Acremonium cellulolyticus and Aspergillus chevialeri. The FTIR spectrum revealed the presence of various functional groups such as amines, amides, carboxylates, alcohols, alkanes, alkynes, nitro groups, etc. The knowledge of these components can be further employed for the production of pharmaceutically important products in due course of time Copyright@ International Science Community Association