International Science Community Association International Research Journal of Biological Sciences 2278-3202 7 9 2018 09 10 Isolation and characterization of cellulose-degrading actinomycetes isolates 12 17 EN Kini Anushri 1 Department of Zoology, VIVA College, Virar, MS, India Salvi Sonal 2 Department of Zoology, VIVA College, Virar, MS, India Mhatre Rutuja 3 Department of Zoology, VIVA College, Virar, MS, India Chavan Kajal 4 Department of Zoology, VIVA College, Virar, MS, India Padhye Shrutika 5 Department of Zoology, VIVA College, Virar, MS, India Khedekar Prakash 6 Department of Zoology, VIVA College, Virar, MS, India Subramanian Smita 7 Department of Zoology, VIVA College, Virar, MS, India Feleke Gebeyehu 1 Department of Biology, Wolaita Sodo University, Ethiopia Patnaik B. Sairam 2 Department of Biology, Wolaita Sodo University, Ethiopia Yi Khin Pyone 1 Molecular Genetics Laboratory, Biotechnology Research Department, Kyaukse, Myanmar Htway Honey Thet Paing 2 Molecular Genetics Laboratory, Biotechnology Research Department, Kyaukse, Myanmar Yu San San 3 Molecular Genetics Laboratory, Biotechnology Research Department, Kyaukse, Myanmar and Microbiology Laboratory, Biotechnology Research Department, Kyaukse, Myanmar > Research Paper 2018 6 28 2018 09 10 A total of twenty-one strains were isolated from various soil sources under wood decaying matter, manure and vegetative fields in the campus of Mandalay Technological University, Mandalay, Myanmar. Among them, eight strains were confirmed as Actinomycetes according to the biochemical examinations, cultural morphology, microscopic morphology and colonial morphology. Their cellulolytic activity was screened by using different types of cellulose substrates such as cellulose powder, CMC powder, acid treated rice straw and base treated rice straw. Quantitative determination was done by DNS reducing sugar analysis method and strains M2, V2 and W1 showed best results in reducing sugar productivity of 0.0504mg/ml using 1% CMC, 0.2100mg/ml using 0.5% cellulose and 0.1596mg/ml using 2% rice straw treated with 2M NaOH respectively. Copyright@ International Science Community Association