International Science Community Association International Research Journal of Biological Sciences 2278 - 3202 6 8 2017 08 10 Detection of Arctigenin in Ipomoea cairica L. leaves: A potential drug for Japanese encephalitis 47 49 EN Shaba A.M. 1 Department of Biological Sciences, Niger State Polytechnic Zungeru, Niger State, Nigeria Oyeleke S.B. 2 Department of Microbiology, Federal University of Technology, Minna, Nigeria Oyewole O.A. 3 Department of Microbiology, Federal University of Technology, Minna, Nigeria Mohammed S.S.D. 4 Department of Microbiology, Kaduna State University, Kaduna State, Nigeria Salahudeen A.O. 5 Department of Microbiology, Federal University of Technology, Minna, Nigeria Ikekwem C.C. 6 Department of Microbiology, Federal University of Technology, Minna, Nigeria Niranjan Nandkumar Patil 1 Department of Microbiology, Patkar-Varde College, S.V. Road, Goregaon, Mumbai, India Shweta Bhise Patel 2 Department of Microbiology, Patkar-Varde College, S.V. Road, Goregaon, Mumbai, India Anup Kumar Sarkar 1 Department of Botany, Dukhulal Nibaran Chandra College, Aurangabad, Murshidabad, Pin-742201, West Bengal, India and Department of Botany, Prasanna Deb Women’s College, Jalpaiguri, Pin-735101, West Bengal, India Manas Dey 2 Jurapani High School, Jurapani, Dhupguri, Jalpaiguri, Pin-735210, West Bengal, India Mallika Mazumder 3 Department of Botany, Raiganj University, Uttar Dinajpur, Pin-733134, West Bengal, India Jalil Ahmad 1 Department of Biological sciences, University of South Asia, Lahore, Pakistan Ayesha Ameen 2 Department of Biological sciences, University of South Asia, Lahore, Pakistan Shahid Raza 3 Department of Biological sciences, University of South Asia, Lahore, Pakistan Victor Singh Ayam 1 Department of Botany, Rajiv Gandhi University, Rono Hills, Itanagar 79111, Arunachal Pradesh, India Pradip Doley 2 Department of Botany, Rajiv Gandhi University, Rono Hills, Itanagar 79111, Arunachal Pradesh, India Ch. B. Singh 3 Institute of Bioresource and Sustainable Development, Takyelpat, Imphal 795001, Manipur, India Maulik Rachh 1 Veer Narmad South Gujarat University, Surat, Gujarat, India Piyush Desai 2 Veer Narmad South Gujarat University, Surat, Gujarat, India Deepa Srivastava 1 Department of Botany, D.D.U. Gorakhpur University, Gorakhpur, Uttar Pradesh, India > Short Communication 2017 1 30 2017 08 10 Ipomoea cairica L. is a perennial herb which grows in unstable sites, such as waste-ground and roadsides in urban areas. It has been reported for several medicinal properties. Literature survey revealed the presence of phenylpropanoid compounds in this plant. One of such compound is Arctigenin. Arctigenin, is a Phenylpropanoid dibenzylbutyrolactone lignan with antinflammatory and antioxidant activities. Recent report suggests that arctigenin inhibits neuronal apoptosis and can reduce the severity of Japanese encephalitis. The presence work confirms the presence of arctigenin in cultivated plant of Ipomoea cairica leaves extract. The dried leaves sample was extracted through column chromatography with ethanol. The extracted samples were subjected to thin layer chromatography (TLC) taking Benzene: Ethyle acetate (9:1 ratio) and high performance liquid chromatography (HPLC) in methanol. Identification of the isolated compounds was done with reference standard using TLC and HPLC. The present study confirms the presence of arctigenin in leaves extract of Ipomoea cairia leaves. Copyright@ International Science Community Association