International Science Community Association International Research Journal of Biological Sciences 2278-3202 10 1 2021 02 10 Current updates on Vaccine with SARS-COV-2 - A review 45 52 EN Shiferaw Legesse 1 Ethiopia Meat and Dairy Industry Development Institute, P.O.1573, Bishoftu, Ethiopia Damise Taye 2 Selale University, College Animal and Range science, P.O. 245, Fiche, Ethiopia Mahajan Minakshi 1 Department of Botany, Fergusson College, Pune-411004, India Hajare Shweta D. 2 Department of Botany, Fergusson College, Pune-411004, India . Riya 1 Biotechnology, School of Pharmaceutical and Health care Sciences, CT University, Ludhiana, India Thapar Parul 2 Biotechnology, School of Pharmaceutical and Health care Sciences, CT University, Ludhiana, India E.E. El Nur 1 Department of Botany, Faculty of Science, University of Khartoum, PC, 11115, P. O. Box 321 Khartoum, Sudan L.I. Ali 2 Department of Botany, Faculty of Science, University of Khartoum, PC, 11115, P. O. Box 321 Khartoum, Sudan E. Fadul 3 Department of Medicinal Biochemistry, Medicinal, Aromatic and Traditional Research Institute (M.A.P.R.I.), National Center for Research, P. O. Box 2404 Khartoum, Sudan l.E. Mohamed 4 Department of Botany, Faculty of Science, University of Khartoum, PC, 11115, P. O. Box 321 Khartoum, Sudan Lumogdang Leonel P. 1 Department of Marine Biology, Southern Philippines of Agri-Business and Marine and Aquatic School of Technology (SPAMAST), Poblacion Malita, Davao Occidental Philippines and College of Arts and Sciences, Xavier University-Ateneo De Cagayan, Cagayan de-Oro Philippines Bullong Lynde Q. 2 Department of Marine Biology, Southern Philippines of Agri-Business and Marine and Aquatic School of Technology (SPAMAST), Poblacion Malita, Davao Occidental Philippines and College of Arts and Sciences, Xavier University-Ateneo De Cagayan, Cagayan de-Oro Philippines Nuneza Olga M. 3 Department of Biological Sciences, Mindanao State University-Iligan Institute of Technology (MSU-IIT), Tibanga, Iligan City Philippines and Department of Chemistry, Mindanao State University-Iligan Institute of Technology (MSU-IIT), Tibanga, Iligan City Philippines Uy Mylene M. 4 Department of Biological Sciences, Mindanao State University-Iligan Institute of Technology (MSU-IIT), Tibanga, Iligan City Philippines and Department of Chemistry, Mindanao State University-Iligan Institute of Technology (MSU-IIT), Tibanga, Iligan City Philippines Khan Amrin 1 School of Studies in Microbiology, Vikram University, Ujjain, MP, 456010, India Jain Sudhir Kumar 2 School of Studies in Microbiology, Vikram University, Ujjain, MP, 456010, India Prakash Sadguru 1 Department of Zoology, MLK Post Graduate College, Balrampur, Uttar Pradesh, India Verma Ashok Kumar 2 Department of Zoology, Government Post Graduate College, Saidabad, Prayagraj, Uttar Pradesh, India Sarkar Roni 1 South Calcutta Girls College, 72, Sarat Bose Rd, Lansdown, Garcha, Ballygunge, Kolkata, West Bengal 700025, India Sakshi Shukla 1 Department of Biotechnology, MRD Life Sciences Pvt. Ltd. Lucknow, India Chitranshu Pandey 2 Department of Biotechnology, MRD Life Sciences Pvt. Ltd. Lucknow, India > Review Paper 2020 6 20 2021 02 10 SARS-CoV-2 pivotal agent of coronavirus disease, initially appeared in China in late December 2019. This has since contaminated in excess of eight lakhs seventy thousands people and gave rise to in excess of forty three thousands deaths worldwide. Here, we explore SARS-CoV-2 prophylactic and therapeutic strategies with prominence on the vaccine production and their obstacles. Vaccines are quickly evolving but would possibly emerge quite late to impact a possible pandemic\'s first wave. Important lessons for the production of vaccines here against quickly evolving viruses, however, may be studied. Importantly, vaccines with SARS-CoV-2 would be necessary to reduce mortality and morbidity if virus is identified in the population. Copyright@ International Science Community Association