International Science Community Association International Research Journal of Biological Sciences 2278-3202 10 1 2021 02 10 Evaluation of the cytotoxicity potential of ethanolic extract of Chrysophyllum cainitousing the brine shrimp lethality bioassay 28 32 EN Shiferaw Legesse 1 Ethiopia Meat and Dairy Industry Development Institute, P.O.1573, Bishoftu, Ethiopia Damise Taye 2 Selale University, College Animal and Range science, P.O. 245, Fiche, Ethiopia Mahajan Minakshi 1 Department of Botany, Fergusson College, Pune-411004, India Hajare Shweta D. 2 Department of Botany, Fergusson College, Pune-411004, India . Riya 1 Biotechnology, School of Pharmaceutical and Health care Sciences, CT University, Ludhiana, India Thapar Parul 2 Biotechnology, School of Pharmaceutical and Health care Sciences, CT University, Ludhiana, India E.E. El Nur 1 Department of Botany, Faculty of Science, University of Khartoum, PC, 11115, P. O. Box 321 Khartoum, Sudan L.I. Ali 2 Department of Botany, Faculty of Science, University of Khartoum, PC, 11115, P. O. Box 321 Khartoum, Sudan E. Fadul 3 Department of Medicinal Biochemistry, Medicinal, Aromatic and Traditional Research Institute (M.A.P.R.I.), National Center for Research, P. O. Box 2404 Khartoum, Sudan l.E. Mohamed 4 Department of Botany, Faculty of Science, University of Khartoum, PC, 11115, P. O. Box 321 Khartoum, Sudan Lumogdang Leonel P. 1 Department of Marine Biology, Southern Philippines of Agri-Business and Marine and Aquatic School of Technology (SPAMAST), Poblacion Malita, Davao Occidental Philippines and College of Arts and Sciences, Xavier University-Ateneo De Cagayan, Cagayan de-Oro Philippines Bullong Lynde Q. 2 Department of Marine Biology, Southern Philippines of Agri-Business and Marine and Aquatic School of Technology (SPAMAST), Poblacion Malita, Davao Occidental Philippines and College of Arts and Sciences, Xavier University-Ateneo De Cagayan, Cagayan de-Oro Philippines Nuneza Olga M. 3 Department of Biological Sciences, Mindanao State University-Iligan Institute of Technology (MSU-IIT), Tibanga, Iligan City Philippines and Department of Chemistry, Mindanao State University-Iligan Institute of Technology (MSU-IIT), Tibanga, Iligan City Philippines Uy Mylene M. 4 Department of Biological Sciences, Mindanao State University-Iligan Institute of Technology (MSU-IIT), Tibanga, Iligan City Philippines and Department of Chemistry, Mindanao State University-Iligan Institute of Technology (MSU-IIT), Tibanga, Iligan City Philippines > Research Paper 2020 7 22 2021 02 10 The Philippines has rich floral biodiversity accompanied with an abundant source of medicinal plants easily accessible in the locality. In terms of ethno-medical properties, Chrysophyllum cainito has been used to treat various diseases. In this study, C. cainito leaves were collected and evaluated for cytotoxicity using the Brine Shrimp Lethality Bioassay. The C. cainito leaves were extracted with water, 50:50 ethanol-water, and absolute ethanol to produce the decoction, hydro-ethanolic, and ethanolic extracts, respectively. Four concentrations (10, 100, 500, 1000& Copyright@ International Science Community Association