Antibacterial activity of Methanolic extract and Semi Alkaloidal Fraction of flower of Sphaeranthus indicus Linn.
- 1Department of Zoology, Moolji Jaitha College, Jalgaon, North Maharashtra University, Jalgaon 425002 M.S. India
- 2Department of Zoology, Moolji Jaitha College, Jalgaon, North Maharashtra University, Jalgaon 425002 M.S. India
- 3Department of Zoology, Moolji Jaitha College, Jalgaon, North Maharashtra University, Jalgaon 425002 M.S. India
- 4Department of Zoology, Moolji Jaitha College, Jalgaon, North Maharashtra University, Jalgaon 425002 M.S. India
Res. J. Recent Sci., Volume 5, Issue (ISC-2015), Pages 16-19, -----Select----,2 (2016)
Many herbal remedies have been used in various medical systems for treating and managing various diseases. The weed Sphaeranthus indicus Linn been used in different systems of traditional medicine for the treatment of disorders and diseases in human beings. The antibacterial potential of flower of S.indicus against seven bacterial pathogens cultures was specifically studied with respect to methanolic extract and semi alkaloidal fraction. Preliminary screening of in vitro antibacterial activity of methanolic extract and semi alkaloidal fraction was carried out by the agar well diffusion method. The highest zone of inhibition was measured against K. pneumoniae (18.60 mm), whereas, least in E. coli (13.83mm) at 1000µg/ml of MeOHx. K. pneumoniae was sensitive at the highest MIC (8 mg/ml) while lowest in E. coli MIC (4 mg/ml) to the SAF.
- Westh H., Zinn C.S. and Rosdahl V.T. (2004)., Aninternational multicenter study of antimicrobialconsumption and resistance in Staphylococcus aureusisolates from 15 hospitals in 14 countries., Microb DrugResist., 10, 169-176.
- Bandow J.E., Brotz H. and Leichert L.I.O. (2003)., Proteomic approach to understanding antibiotic action.Antimicrob Agents Chemother., , 47, 948-955.
- Rojas R., Bustamante B. and Bauer J. (2003)., Antimicrobial activity of selected Peruvian medicinalplants., J Ethnopharmacol., 88, 199-204.
- Benkeblia N. (2004)., Antimicrobial activity of essentialoil extracts of various onions (Allium cepa) and garlic(Allium sativum)., Lebensm-Wiss u-Technol., 37, 263-268.
- Parekh J. and Chanda S. (2007)., In Vitro antibacterialactivity of crude methanol extracts of Woodfordiafructicosa kurz flower (Lythraceae)., Brazilian JMicrobiol., 38,204-207.
- Krishnaraju A.V., Rao T.V.N. and Sundararaju D.(2005)., Assessment of bioactivity of Indian medicinalplants using Brine shrimp (Artemia salina) lethalityassay., Inter J Appl Sci Eng., 2,125-134.
- Tanaka H., Sato M. and Fujiwara S. (2002)., Antibacterial activity of isoflavonoids isolated fromErythrina variegata against methicillinresistantStaphylococcus aureus., Lett Appl Microbiol., 35, 494-498
- Naqvi S.B. (1997)., Studies on antibacterial activity ofcompounds of plants origin and isolation of activecomponents from Sphaeranthus indicus Linn, Ph Dthesis, , University of Karachi, Karachi, Pakistan.
- Chopda M.Z. (2009)., Studies on the wound healingagents of plant origin (Unpublished doctoraldissertation)., Moolji Jaitha College, North MaharashtraUniversity, Jalgaon, Maharashtra, INDIA.
- Srinivasan D., Perumalsamy L.P., Nathan S. and Sures T.(2001)., Antimicrobial activity of certain Indianmedicinal plants used in folkloric medicine., JEthnopharm., 94, 217-222.
- Zachariah S.M., Pappachen L.K., Aneesh T.P., Alex L.,Sumith G., John M.S., Praseetha M.C. and NagalekshmiR. (2010). Phytochemical and pharmacological screeningof Sphaeranthus indicus Linn for antimicrobial activity., IJPSR., 1(10), 169-173., undefined
- Khare C.P. (2004)., Encyclopedia of Indian Medicinalplants. Springer-Verlag, , Berlin Heidelberg New York.
- Chopda M.Z., Patole S.S. and Mahajan R.T. (2010)., Wound healing activity of Sphaeranthus indicus (Linn)in Albino rats, Bioresources for Rural Livelihood: Editedby: G.K. Kulkarni, B.N. Pandey and B.D. Joshi,Narendra Publishing House, , I, 239-244.