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Potentiometric analysis of Dimethyl Sulfoxide, Di-n-octyl Sulfoxide, Diphenyl Sulfoxide, p-di-tolyl Sulfoxide and Indium Complex of Diphenyl Sulfoxide in Non Aqueous Solvents

Author Affiliations

  • 1Department of Chemistry, Brijlal Biyani Science College, Amravati, Maharashtra, India

Res. J. Recent Sci., Volume 5, Issue (ISC-2015), Pages 108-114, -----Select----,2 (2016)

Abstract

In medicine Dimethyl Sulfoxide is predominantly used as a topical analgesic, a vehicle for topical application of pharmaceuticals, as an anti-inflammatory, and an antioxidant. This paper deals with Potentiometric Analysis of Dimethyl Sulfoxide, Di-n-octyl Sulfoxide, Diphenyl Sulfoxide, p-di-tolyl Sulfoxide and Indium Complex of Diphenyl Sulfoxide in Non Aqueous Solvents such as sulphuric acid, phosphoric acid, glacial acetic acid and acetic anhydride. In present analysis two types of potentiometric titrations Oxidation-Reduction and Acid-Base titrations in nonaqueous solvents have been performed, and interest is focused upon changes in the e.m.f. of an electrolytic cell as a titrant of precisely known concentration is added to a solution of the analyte. OSAW direct reading potentiometer was used to carry out redox titrations using platinum and saturated calomel electrodes. The pH-titrations were made with an ELICO LI-10 pH-meter in conjunction with Glass (EM-42) and calomel (ER-70) electrodes. An end point is located more precisely by plotting successive values of the rate of change of cell e.m.f. vs each increment of titrant in the vicinity of the inflection point. The position of the maximum on the first derivative curve corresponds to the inflection point on the normal titration curve. Fairly accurate results with high degree of precision are observed.

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