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Applications of Lipopeptide(s) from a Bacillus sp: An Overview

Author Affiliations

  • 1Department of Biotechnology Himachal Pradesh University Summer Hill, Shimla, India
  • 2Department of Biotechnology Himachal Pradesh University Summer Hill, Shimla, India
  • 3Department of Biotechnology Himachal Pradesh University Summer Hill, Shimla, India
  • 4Department of Biotechnology Himachal Pradesh University Summer Hill, Shimla, India

Res. J. Recent Sci., Volume 5, Issue (11), Pages 50-54, November,2 (2016)

Abstract

In the recent years, continuous and excess use of chemical pesticides in the field has created an adverse ecological balance that affected the whole environment. Most of the part of crops is destroyed by the phytopathogens such as fungi, bacteria and yeast causes to economic losses to the farmers. Extensive use of the chemicals for controlling the plant diseases in the field has unbalanced the delicate environmental harmony of the fertile land, causes soil water contamination, evolution of new races of microorganisms and risk for humans health. The constant and continue demand for new bio-therapeutic agents with an effective mode of action has activated the intensive/deep research in the field of diverse natural bioactive molecules having antimicrobial activity. Among these active molecules, lipopeptide(s) are a unique class of bio-active secondary metabolites with increasing scientific, therapeutic and biotechnological interest. Bacillus subtilis produced mainly a four different types of lipopeptides with a potential for biotechnological and biopharmaceutical applications. Among the all Lipopeptide(s) classes, Iturin and Surfactin shows attractive antibiotic properties. The main family of the microbial lipopeptide(s) is surfactin, which mainly originated from the B. subtilis. These properties of the surfactin make a momemtous drug (surfactin) for the resolution of a number of global issues in medicine. Cancer and phytopathogens are the major problem in the today’s scenario. The bacterial lipopeptide(s) have lower toxicity for plants and animals, high biodegradability, low irritancy and compatibility with human skin.

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