Evaluation of Antimicrobial Activities of Antibiotics from Marine-derived Fungi
- 1KMCH College of Pharmacy, Coimbatore-641046, Tamil Nadu, India
Res. J. Recent Sci., Volume 5, Issue (10), Pages 36-38, October,2 (2016)
Many microorganisms have been isolated and used as antibiotics against infections caused by other microorganisms because of their antimicrobial activities. Fungi are one of these microorganisms which have been isolated and evaluated for their antimicrobial activities. The objective of this study was to isolate fungi from marine sediments collected from the coastal regions of Ponnani and Chavakad of Kerala, India, and to evaluate their effects as antibiotics. Ten soil samples have been collected from different spots in the same area, serially diluted, maintained on starch casein agar slants by frequent sub-culturing and then spread on potato dextrose agar and nutrient agar media using streak plate method. Five isolates designated as AM1, AM2, AM3, AM4, and AM5 were evaluated for their antimicrobial activities. Out of the five isolates selected, only two strains AM2 and AM5 have shown good antibacterial activity against Staphelococcus aureus, Basilus subtilis, Salmonella typhi, and E.coli. The isolate AM5 exhibited more antibacterial activity than the isolate AM-2, and hence selected for further studies.
- Hawksworth D.L. (1991)., The fungal dimension of biodiversity: magnitude, significance, and conservation., Mycological research, 95(6), 641-655.
- Ho W.H., To P.C. and Hyde K.D. (2003)., Induction of antibiotic production of freshwater fungi using mix-culture fermentation., Fungal Diversity., 2003, 12, 45-51.
- Bizuye A., Moges F. and Andualem B. (2013)., Isolation and screening of antibiotic producing actinomycetes from soils in Gondar town, North West Ethiopia., Asian Pacific Journal of Tropical Disease, 3(5), 375-381.
- Kuamr Ritesh, Shrivastav A.K., Singha A.K., Kumar P. and Nirmala A. (2012)., Antibiotic production from marine Strptomycyes sp., Int J Pharm Bio Sci, 3(4), 331-342.
- Das P., Mukherjee S. and Sen R. (2008)., Antimicrobial potential of a lipopeptide biosurfactant derived from a marine Bacillus circulans., Journal of applied microbiology, 104(6), 1675-1684.
- Prasad S. and Smith P. (2013)., Meeting the threat of Antibiotic Resistance: building a new frontline defence., Office of the Chief Scientist.