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The prevalence of circulating Anti- sperm Antibodies in Male serum of infertile couples in Khartoum State Sudan

Author Affiliations

  • 1Department of Immunology, Faculty of Medical Laboratory Sciences, National Ribat University, University in Omdurman, SUDAN
  • 2Department of Biochemistry, Faculty of Medicine and Health Sciences, University of Dongola, SUDAN

Res. J. Recent Sci., Volume 5, Issue (1), Pages 48-50, January,2 (2016)


Anti-sperm antibodies are the one of cause of immunological infertility, as they impair sperm function by binding to the sperm membrane. This objective of the study was to determine the prevalence of anti-sperm antibodies in males of infertile couples in Khartoum State. The study was carried out at (June 2012 to April 2013) to determine the prevalence of anti-sperm antibodies in males of infertile couples suffering from primary and secondary infertility attended to Reproductive Health Care Centre in Khartoum State. The total numbers of study group were (86) couples, their ages ranged (15-55) years with the main ages group were (35) years. Blood samples were collected from males to examine the present of anti-sperm antibodies in male of infertile couples. Serum levels of anti-sperm antibodies quantitavely were measured using (ELISA) kits. The presence anti-sperm antibodies were low among infertile males. The results test revealed that (3) subjects with percentage (3.5%) serum samples of infertile males were positive for anti-sperm antibodies, while (83) subjects with percentage (96.5%) were negative for the presence of anti-sperm antibodies. Negative values were recorded if the value of test was < 60 RU/ml. We concluded that Sudanese infertile males have low serum level of (ASA) that may be the reason of infertility among infertile couple due insignificant. The serum (ASA) is more common observed in male with higher viscosity and agglutinated semen fluid in physical examination, among population of the study. Also it found that no relations between microscopically examination and presence of (ASA) in infertile male.


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