International E-publication: Publish Projects, Dissertation, Theses, Books, Souvenir, Conference Proceeding with ISBN.  International E-Bulletin: Information/News regarding: Academics and Research

Antimicrobial Activity of root extract of Phyllanthus fraternus Webster: An Ethnomedicinal plant

    , ,

Author Affiliations

  • 1Mehsana Urban Institute of Science, Ganpat University, Kherwa, Dist. Mehsana, North Gujarat, INDIA
  • 2M.G. Science Institute, Dadasaheb Mavlankar Campus, Navarangpura, Ahmedabad, Gujarat, INDIA

Res. J. Recent Sci., Volume 3, Issue (ISC-2013), Pages 275-278, (2014)

Abstract

Phyllanthus fraternus Webster, a pan tropical weed originated from western India, belongs to family Euphorbiaceae and commonly known as “Bhumyamlaki”. It is a medicinally very useful plant species which is frequently used by tribal of Gujarat to cure certain diseases like asthma, cough, diarrhea, diabetes, skin diseases and scabies. Current study is targeted the on the activity of antimicrobial metabolites from the root. Root were dried and extracted by methanol. This root extract of Phyllanthus fraternus was screened against eleven clinically important bacterial strains and three antifungal strain by disc diffusion method. Result showed maximum antibacterial activities against P.aeruginosa with zone of inhibition of 25 mm followed by S. typhiB with a zone of inhibition of 11 mm and minimum against S. typhi Awith zone of inhibition of 10 mm. Similarly the maximum antifungal activity was noted against A. niger (10 mm). Absolute methanol was used as control during the experiments. This indicates that antimicrobial activities may be due to presence of secondary metabolites. Hence, the plant can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities. As the antimicrobial work has been not carried out so far on Phyllanthus fraternus,

References

  1. Prasannabalaji N., Muralitharan G., Sivanandan R.N., Kumaran S. and Pugazhvendan S.R., Antibacterial activities of some Indian traditional plant extracts, Asian Pacific J. tropical Disease, S291-S295, (2012)
  2. Anonynous, World Health Organisation summary of WHO guidelines for the assessment of herbal mediocines,Gram., 28, 13-14 (1993)
  3. Baker J.T., Borris R.P. and Carte B., Natural product drug discovery and development. New perspective on international collaboration, J. Nat. Prod., 58, 1325-1327 (1995)
  4. Pavithra P.S., Janani V.S., Charumathi K.H., Indumathy R., Sirisha Potala and Rama S. Verma; Antibacterial activity of plants used in herbal medicine, International Journal of pharmacy, 24-27 (2010)
  5. Parekh J. and Chanda S., In vitro screening of antibacterial activity of aqueous and alcoholic extracts of various Indian plant species against selected pathogens from Enteriobacteriaceac, Afr. J. Microbiol. Res.,1(6), 92-99, (2007), 275-278 (2014)
  6. Bashir Sajid, Erum Alia, Rizwana Kausar, Saleem Uzma, Umme Ruqia-Tulain and Alamgeer, Antimicrobacterial activity of some ethno-medicinal plants used in Pakistan, Res in Pharm, 2(1), 42-45 (2012)
  7. Manal Ismail A., Musa H.A., Yousif K.H. and Sabahelkhier M.K., Investigation Antibacterial Activity Extraction from two Medicinal Plants Available in Sudan, Res. J. Recent Sci.,2(10), 6-9 (2013)
  8. Edeoga H.O., Okwu D.E. and Mbaebie B.O., Phytochemical constituents of some Nigerian medicinal plants. Afr. J. Biotech, 4, 685-688 (2005)
  9. Mehta Kavit, Patel B.N. and Jain B.K., Phytochemical analysis of leaf extract of Phyllanthus fraternus, Res. J. Recent Sci.,2(1), 12-15 (2013)
  10. Abo K.A., Ogunleye V.O. and Ashidi J.S., Antimicrobial potential of Spondias mombin, Croton zambesicus and Zygotritonia crocea, Phytotherapy Research, 13, 494-497 (1999)
  11. Jain Monica, Rajput Ritika and Mishra Anamika, Enhancement of secondary Metabolite Biosynthesis inBacopa monnieri: An in vitro Study, Res. J. Recent Sci.,2(1), 13-16 (2013)
  12. Minuta L., Journal of public health and biological sciences,1(3), 74-78 (2012)
  13. Javed Ahmad, Iffat Khan, Ashfaq Ahmad and kaushar Imam, In Vitro Antioxidant and Antimicrobial Activity of Methanolic root Extracts of Hyptis suaveolens, Res. J. Recent Sci.,2(1), 41-46 (2013)
  14. Lubna Tahir and Naeem Khan, Antibacterial potential of crude leaf ,fruit and flower extracts of Tagetes, Afr.J.Biotech,1(2),(2009)
  15. More S.M., Shinde V.A., Khan Saiqua, Girde A.V. and Pawar V.N., Antimicrobial Activity of Phospholipid Compound Produced by Acidophilic Bacillus subtilis Isolated from Lonar Lake, Buldhana, India Res. J. Recent Sci.,1(11), 22-26 (2012)
  16. Sujatha S. Complementary and alternative therapies in palliative care:A transtition from modern medicine to traditional medicine in india, J Cancer Pain Symptom Palliation,1, 25-9 (2005)
  17. Sukanya S.L., Sudisha J., Hariprasad P., Niranjana S.R., Prakash H.S. and Fathima S.K., Antimicrobial activity of leaf extracts of Indian medicinal plants against clinical and phytopathogenic bacteria, Afr. J. Biotech.,8(23), 6677-6682 (2009)
  18. Uzun Y., Keles A., Imali A., Ogun E and Kaya A., Antimicrobial activity of Urtica dioica L. and Rheum ribesL., Bioscience Res. Bulle, 18, 43-50 (2002)
  19. Vashist H. and Jindal A., Antimicrobial activities of medicinal plants- review. Inter, J. Res. Pharm. Biomed. Sci., 3(1), 222-224 (2012)
  20. Veeramuthu D., Muniappan A. and Savarimuthu I., Antimicrobial activity of some ethno medicinal plants used by Paliyar tribe from Tamil nadu, India, BMC Complementary and Alternative Medicine, 6, 35, (2006)