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Terpenes and Antimicrobial Activity from Lantana Camara Leaves

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Author Affiliations

  • 1 Department of chemistry, A.V.V.M. Sri Pushpam College, Poondi, Thanjavur-613 503, Tamil Nadu, INDIA
  • 2 School of Chemical and Biotechnology, Department of Chemistry, SASTRA University, Thanjavur, Tamil Nadu, INDIA

Res. J. Recent Sci., Volume 3, Issue (9), Pages 52-55, September,2 (2014)

Abstract

The plant leaves contain a number of medicinally important compounds. The present study was carried out to identify the saturated terpenoid alkane, triterpenoid and evaluate antimicrobial activity of hexane extract of Lantana camara leaves. The terpenoids were separated from hexane crude extract by using column chromatography and Thin layer chromatography. Column chromatography was eluted with hexane, chloroform solvent mixtures of increasing polarity. The structures of this isolated compound were identified on the basis of spectral analysis. i.e. FT-IR, H’NMR, 13CNMR, EI/MS. Terpene characterization using various spectroscopic analysis the final identified terpene as Calarane and 3-hydroxy-10,19-en-urs-28-oic acid. The antimicrobial activity was determined by well diffusion method and tested against different pathogens of three bacteria and two funguses. Antimicrobial activity of 50, 100 and 150% Hexane extract of Lantana camara leaves has been evaluated against streptococcus pneumoniae, Aspergillus niger, Salmonella typhi, klebsiella pneumoniae, Trichophyton Violaceum. In 150% concentration of hexane extract showed the highest antibacterial zone against streptococcus pneumoniae. In 100% and 150% concentration the extract showed the highest antimicrobial zone against Aspergillus niger. This is the first report of the isolation and identification of above compound from hexane extract of Lantana camara leaves

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