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Anticancer activity of Ethanol extract of Polygala javana DC whole Plant Against Dalton Ascites Lymphoma

Author Affiliations

  • 1Government Siddha Medical College, Palayamkottai, Tamil Nadu, INDIA
  • 2 Ethnopharmacology Unit, Research Department of Botany, V.O. Chidambaram College, Tuticorin- 628008, TN, INDIA

Res. J. Recent Sci., Volume 2, Issue (2), Pages 18-22, February,2 (2013)

Abstract

The present study aims to evaluate the antitumor activity of ethanol extract of whole plant of Polygala javana on DAL model in Swiss Albino mice. Evaluation of the antitumor effect of ethanol extract of whole plant of Polygala javana on tumor growth and hosts survival time was made by the study of the following parameters: tumor volume, viable and non viable cell count and life span of host. The results showed decrease in tumor volume and cell viability. Hematological studies revealed that, the Hb count decreased in DAL treated mice, whereas, it was induced by the drug treated animals and showed an increase in Hb near to normal levels. The results suggeste that, the extracts of whole plant of Polygala javana exhibited significant antitumor activity on DAL bearing mice.

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