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Synthesis, characterization and Biological studies of Cu(II) and Ni(II) complexes with New Bidentate Shiffs base ligands as 4-hydroxy-3-(1-(arylimino)ethyl)chromen-2-one

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Author Affiliations

  • 1Department of Chemistry, PG Department of Chemistry and Research Centre N.S.B. College, Nanded, INDIA

Res. J. Recent Sci., Volume 1, Issue (ISC-2011), Pages 110-116, (2012)

Abstract

New Bidentate Shiff's base ligands 4-hydroxy-3-(1-(arylimino)ethyl)chromen-2-one were synthesized by condensation of primary aromatic amines with 3-acetyl-4-hydroxychromen-2-one. These were characterized by IR, 1HNMR, 13CNMR and mass spectral analysis. Cu(II) and Ni(II) complexes were synthesized and characterized by their mass, IR, electronic and XRD spectral analysis. Magnetic moments and molar conductance properties were studied using standard methods. Octahedral geometry around these metal ions has been proposed on the basis of magnetic and spectral studies. In vitro biological screening effects of the investigated compounds were tested against the bacterial species Staphylococcus aureus, Escherichia coli, Salmonella typhi and Bacillus subtilis by Agar cup method. Fungal species Aspergillus niger, Penicillium chrysogenum, Fusarium moneliforme and Aspergillus flavus by the posion plate method. A comparative study of inhibition values of the Schiff base ligands and their complexes indicates that the complexes exhibit higher antimicrobial activity than the free ligands.

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