Synthesis, Antimicrobial and Insecticidal Activity Studies of 5-Nitro N-[Arylidenhydrazidomethyl Indole] 2-(Substituted Aryl)-3-(N-Indolyl Acetamiddyl)-4-Oxothiazolidines
Author Affiliations
- 1 Department of Chemistry, J.N. College of Technology, Bhopal M.P. INDIA
Res. J. Recent Sci., Volume 1, Issue (ISC-2011), Pages 99-104, (2012)
Abstract
Several 5nitro N'-(arylidine hydrazidomethyl) indole were prepared by conensing N'-indolyl acetyl hydrazine with different type of aromatic aldehydes. 2-(substituted aryl)-3-(N'-5-nitro indole acetamiddyl)-4-oxo-thiazolidines were prepared by condensing N'-(arylidine hydrazidomethyl)-indoles with thioglycollic acid.The IR and 1HNMR spectral studies have confirmed the structures of these synthesized compounds.The synthesized compounds which have also been tested for their antimicrobial activity against S. aureus, B.megaterium and A. niger and A. Paraciticus.
References
- Gadaginamath G.S., Shyadligeri A.S. and Kavali R.R, Indian J. Chem. 38(B), 156(1999)
- Renukadevi P. and Biradar J.S., Indian J. Heterocyclic Chem., (9), 107(1999)
- Hogle M.B. , Uthale A.C., Indian J. Chem., 29(B), 390 (1990)
- Oza H., Joshi D. and Prakash H., Indian J. Chem., 37(B), 882 (1998)
- Lodhi R.S. and Shrivastava S.D., Indian J. Chem., 36(B) 947 (1997)
- N.C. Desai and G.D. Vyas et al., Indian J. Chem., 39(B), 277 (2000)
- Dutta M.M., Goswami B.N., Kataky J.C.S. J. Indian Chem., Soc., 67, 322 (1990)
- Lassagra B.P., Bhatt H.H. and Parikh A.R., Indian J. Hetero Cyclic Chem., 1, 10 ( 2000)
- Mishra S. and Shrivastava S.D., Indian J. Chem., 38(B), 826 ( 1997)
- lather V. and Chowdary P.V.R., Indian J. Pharma. Sci.,65(6), 576 (2003)
- Vogels Text Book of Practical organic Chemistry fifth Edition, 1161 Third Indian reprint,(2005)
- Collias C.H., A text book of “Microbial metho” Buffer worth, London, 9, 364 (1967)
- Robert M. Silverstein, A text book of “Spectroscopic Ientification of organic Compouns” IIn. Eition, John wiley and sons, (1967)
