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Vermifugal Activity of Biofabricated Silver Nanoparticles

Author Affiliations

  • 1Rajiv Gandhi Chair, Cochin University of Science and Technology, Kochi, Kerala, INDIA
  • 2 School of Environmental Studies, Cochin University of Science and Technology, Kochi, Kerala, INDIA
  • 3 Microbiology, Fermentation and Biotechnology Division, Central Institute of Fisheries Technology, Kochi, Kerala, INDIA
  • 4 Department of Chemical Oceanography, Cochin University of Science and Technology, Kochi, Kerala, INDIA
  • 5 Soil Science Department, Kerala Forest Research Institute, Peechi, Thrissur, Kerala, INDIA

Res. J. Recent Sci., Volume 1, Issue (ISC-2011), Pages 47-51,(2012)

Abstract

Nanotechnology is an area of extensive research in recent years. Applications of noble metals have increased throughout human civilization and noble metal nanoparticles have benefited multiple sectors using their nano-scale applications. The possibility of using plants in the deliberate synthesis of nanoparticles is a recent phenomenon. Helminth infections are among the most common infections in humans, affecting a large population of the World. As per WHO, only few drugs are frequently used in the treatment of these parasite infections. Preliminary investigations were carried out to assess the vermifugal actvity of biological silver nanoparticles in-vitro. Albendazole and piperazine citrate were used as standard reference drugs and normal saline as control. Various concentrations of silver nanoparticles and aqueous extract of Hibiscus rosasinensis were tested as per standard protocols. Silver nanoparticles exhibited significant antihelminthic activity as compared to standard.

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