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Samarium (II) Iodide Mediated Synthesis of 3,5-dimethyl-hexahydrocyclopenta[b]furnan-2-one

Author Affiliations

  • 1 Dept. of Chemistry, Faculty of Science and Science Education, Kano University of Science and Technology, Wudil, Kano, NIGERIA

Res. J. Recent Sci., Volume 1, Issue (7), Pages 87-89, July,2 (2012)

Abstract

Selective reduction of the aldehyde of (157) with sodium borohydride gave the alcohol (243) with an excellent yield of 80%.The alcohol was then converted to alkyl Iodide which was readily reduced with SmI2 in NiI2 to give carbocyclic compound (220) with overall yield of 74%. The structures of these products were determined using 1H NMR, 13C NMR, Mass spect. andIR analysis

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