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A Review on efficacy of Azadirachta indica A. Juss based biopesticides: An Indian perspective

Author Affiliations

  • 1 Dept. of Zoology, Raiganj Surendranath Mahavidyalaya, Raiganj, Uttar Dinajpur, West Bengal, INDIA
  • 2 Dept. of Botany, Netaji Mahavidyalaya, Arambagh, Hooghly, West Bengal, INDIA

Res. J. Recent Sci., Volume 1, Issue (3), Pages 94-99, March,2 (2012)


Although both synthetic and natural of pesticides are used extensively in the agricultural fields to control crop pests, it is well known that natural pesticides are eco- friendly and are safe to the non target organisms. The Azadirachta indica A. Juss (neem tree), has long been recognized for its insecticidal properties. Nearly 550 insect pest species are sensitive to azadirachtin, an active compound extracted from the A. indica tree. Nowadays pesticides from A. indica become very much popular because of their biodegradability, least persistence and least toxic to non-target organisms, economic and easy availability. In India, neem products are effective against various pests of both crop fields as well as stored grains like rice, wheat, corn, legumes, potato, tomato, etc. This review put a light on the use and efficacy of A. indica based pesticides against various pests of both crop fields as well as stored grains of India.


  1. Ansari B.A. and Kumar K., Cypermethrin toxicity Effect on the carbohydrate metabolism of the Indian catfish, Hetropneustes fossilis, The Sci. Total Environ., 72, 161-166 (1988)
  2. Singh R., Singh B. and Verma R.A., Efficiency of different indigenous plant products as grain protectent against Callosobruchus chinensis Linn. on pea., Indian J. Entomol., 63,179-181 (2001)
  3. Harikrishnan R., Rani M.N. and Balasundaram C., Hematological and biochemical parameters in common carp, Cyprinus carpio, following treatment for Aeromonas hydrophila infection, Aquacult. 221, 41-50 (2003)
  4. Anuradha A. and Annadurai R.S., Biochemical and molecular evidence of azadirachtin binding to insect actins, Curr. Sci., 95 (2008)
  5. Anon, The wonder of neem, Far Eastern Agriculture, July/August, 17-18 (1992)
  6. Salako E.A., Plant protection for the resource-poor farmers. A keynote address at Nigerian Society for Plant Protection. 30th Annual conference. UNAAB, Abeokuta Sept. 1st-4th, 2002 (2002)
  7. Khalid S. and Shad R.A., Potential advantage of recent allelochemical discoveries and agro cosystems, Prog. Farm. 11, 30-35 (2002)
  8. Fulekar M.H., Environmental Biotechnology. Oxford and IBH Publishing Co. Pvt. Ltd. New Delhi (2005)
  9. Barceloux D., Medical Toxicology of Natural Substances, John Wiley & Sons, Inc. (2008)
  10. Garg D.K., Certain parasites and predators of crop pests in hilly regions of Uttar Pradesh, J. of Appl. Zool. Res.,, 55-56 (1996)
  11. Gupta S.P., Prakash A. and Rao J., Bio-pesticidal activity of certain plant products against rice earhead bug , Leptocorisa acuta Thunb, J. of Appl. Zool. Res., (2), 55-58 (1990)
  12. Mohan K., Gopalan M. and Balasubramanian G., Studies on the effects of neem products and monocrotophos against major pests of rice and their safety to natural enemies. Indian J. Plant Protec., 19, 23-30 (1991)
  13. Krishnaiah N.V. and Kalode M.B., Efficacy of selected botanicals against rice insect pests under green house and field conditions, Indian J. of Plant Protec., 18, 197-205 (1990)
  14. Schmutterer H., Saxena R.C. and Heyde J., Von Der., Morphogenetic effects of some partially purified fractions and methanolic extracts of neem seeds on Mythimna separate Walk, Cnaphlocrosis medi nalis Guen. Zeitschrift fur Agwandt. Entomol., 95, 230-237 (1983)
  15. David P.M.M., Effect of slow release nitrogen fertilizers and the foliar spray of neem products on rice pests, Madras Agricult. J., 73, 274-277 (1986)
  16. Saxena R.C., Justo H.D. and Rueda, B.P., Neem seed bitters for management of plant hopper and leaf hopper pests of rice, Mid-Term Appraisal Works on Botanical Pest Control in Rice Based Cropping systems, 19 (1987)
  17. Sontakke B.K., Field efficacy of insecticide alone and in combination with neem oil against insect pests and their predators in rice., Indian J. Entomol., 55, 260-266 (1993)
  18. Saxena R.C., Epicnoc P.B., Tu C.W. and Puma B.C., Neem Chinaberry and custard apple: antifeedant and insecticidal effects of seed oils on leaf hopper and plant hopper pests of rice, Proc. II. Intn. Neem Conf.,Rauisch- Holzhousen Castle FRG, 403-412 (1984)
  19. Ramraju K. and Sundara Babu P.C., Effect of plant derivatives on brown plant hopper (BPH) and white backed plant hopper (WBPH) nymphs emergence in rice, Internat. Rice Res. Newslett., 14, 30 (1989)
  20. Senthil Nathan S., Choi M.Y., Paik C.H., Seo H.Y., Kim J.D. and Kang S.M., The toxic effects of neem extract and azadiractin on the brown planthopper, Nilaparvatha lugens (Stal), Chemosphere, 67, 80 88 (2007)
  21. Sharma H.C., Sankaram A.V.B., Nwanze K.F. and Singh P.P., Utilization of natural pesticides derived from neem and custard apple in integrated pest management, in Azadirachta indica A. Juss., oxford and IBH Pub. Co. Pvt. Ltd., New Delhi, India, 199-213 (1999)
  22. Reed D.K. and Reed G.I., Control of vegetable insects with neem seed extracts. Proc. Indian Acad. Sci. 94: 335-339 (1985)
  23. Siddappaji C., Kumar A.R.V. and Gangadhar R., Evaluation of different insecticidal sprays against the chickpea borer, Heliothis armigera Hubn. Pesticides, 20, 13-16 (1986)
  24. Nelson S.J., Sundarababu P.C., Rajavel D.S., Srimmannarayana G. and Geetanjali Y., Antifeedant and growth inhibiting effects of azardirachtin-rich neem fractions on Sogatella furcifera Horvath, Spodoptera litura Fabr. and Helicoverpa armigera Hubn, World Neem Conference,10 (1993)
  25. Atwal A.S. and Pajni H.R., Preliminary studies on the insecticidal properties of drupes of Melia azadirachta against caterpillars of Pieris brassicae Linn, Indian J. Entomol., 26, 221-227 (1964)
  26. Mani A., Kumudanathan K. and Jagadish C.A., Relative efficacy of neem oil and endosulfan against insect pests of mustard. Neem News Lett., , 129-131 (1990)
  27. Singh K. and Sharma P.L., Studies on anti-feedant and repellant qualities of neem against aphid,Brevicornye brassicae Linn. on cauliflower and cabbage, Res. and Development Report, 3, 33- 35 (1986)
  28. Ketkar C.M., Use of neem (Azadirachta indica A Juss) and its by products in organic farming, In: Kleeberg, H. and C. P.W., Zebitz (Ed.) Practice Oriented Results on Use and Production of Neem - Ingredients and Pheromones, Proceedings of the 9th Workshop; Hohensolms, Germany, March 13. 15. 2000, 31-38 (2003)
  29. Prakash A., Rao J. and Nandagopal V., Future of Botanical Pesticides in rice, wheat, pulses and vegetables pest management, J. Biopesticds., , 154 169 (2008)
  30. Ketkar C.M., Use of tree-derived non-edible oils as surface protectants for stored legumes against Callosobruchus maculatus and C. chinensis. In:Schmutterer, H. and Ascher K.R.S. (Ed.). Natural pesticides from the neem treeAzadirachta indica A. Juss) and other tropical plants, Proceedings of the Third International Neem Conference, 10- 15 Jul 1986, Nairobi, Kenya. Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ) GmbH., Eschborn, Germany 535-542 (1987)
  31. Golob P., Webley D.J., The use of plants and minerals as traditional protectants of stored products, Report, Tropical Products Institute G138, England, 32 (1980)
  32. Lal S., Saving grain after harvest, In:Kasturi, G. (Ed.) The Hindu Survey of Indian Agriculture 1988, National Press, Madras, India, 246-248 (1988)
  33. Ketkar C.M., Utilization of neem (Azadirachta indica Juss) and its bye-products, Directorate of Non-edible Oils & Soap Industry, Khadi & Village Industries Commission, Bombay, India, 234 (1976)
  34. Muda A.R., Utilization of neem as a pest control agent for stored paddy, In:Proceedings of the 7th Asean Technology Seminar on Grain Post-Harvest Technology, ASEAN Crops Post-Harvest Programme and Asean Food Handling Bureau, Manila, Philippine, 117-178 (1984)
  35. Jilani G. and Amir P., Economics of neem in reducing wheat storage losses: policy implications, Technical Bulletin 2. Southeast Asian Regional Center for Graduate Study and Research in Agriculture, College, Laguna, Philippines. 15 (1987)
  36. Jotwani M.G. and Sircar P., Neem as a protectant against bruchid Callosobruchus maculatus (Fabricius) infesting some leguminous seeds. Indian J. Entomol., 29, 21-24 (1967)
  37. Rahim M., Biological activity of azadirachtin-enriched neem kernel extracts against Rhyzopertha dominica (F.) (Coleoptera: Bostrichidae) in stored wheat, J. Stored Prod. Res.,34,123-128 (1997)
  38. Verma S.P., Singh B. and Singh Y.P., Studies on the comparative efficacy of certain grain protectants against Sitotroga cerealella Oliver. Bull. Grain Technol, 24, 37-42 (1985)
  39. Deshpande A.D., Neem as a protectant against storage pests, M.Sc. thesis, Indian Agric. Res. Inst., New Delhi, India, (1967)
  40. Attri B.S. and Prasad G.R., Studies on the pesticide value of neem oil by-products. Pestology, , 16-20 (1980)
  41. Jotwani M.G. and Sircar P., Neem seed as a protectant against stored grain pests infesting wheat seed, Indian J. Entomol., 27, 199-202 (1965)
  42. Yadav T.D., Studies on the insecticidal treatment against bruchids Callosobruchus maculatus (Fab.) and C. chinensis (Linn.) damaging stored leguminous seeds, Ph.D. thesis, Univ. of Agra, India (1973)
  43. Ali S.I., Singh O.P. and Misra U.S., Effectiveness of plant oils against pulse beetle, Callosobruchus chinensis Linn. Indian J. Entomol., 45, 6-9 (1983)
  44. Pereira J., The effectiveness of six vegetable oils as protectants of cowpeas and bambara groundnut against infestation by Callosobruchus maculatus (F.), J. Stored Prod. Res. 19, 57-62 (1983)
  45. Sharma R.N., Nagasampagi B.A., Bhosle A.S., Mulkarni, M.M. and Tungikar V.B., 'Neemrich': the concept of enriched fractions from neem for behavioral and physiological control of insects, In: Schmutterer, H. Ascher, K.R.S. (Ed.) Natural Pesticides from the Neem Tree (Azadirachta indica A. Juss) and Other Tropical Plants. Proc. 2nd Int. Neem Conf., Rauischholzhausen, Germany, 1983, 115-128 (1984)
  46. Radwanski, S. A., Multiple land utilization in the tropics: an integrated approach with proposals for an international neem tree research and development program. In:Schmutterer, H., K. R. S. Ascher, and H. Rembold (Ed.) Natural pesticides from the neem tree ( Azadirachta indica A. Juss). Proceedings of the First International Neem Conference, 16-18 Jun 1980, Rottach-Egern, German Agency for Technical Cooperation (GTZ), Federal Republic of Germany, 267-278 (1982)
  47. Shukla A., Pathak S.C. and Agrawal R.K., Efficacy and economics of some insecticides and plant products against the infestation of okra shoot and fruit borer, Earis vittella Fab. Crop Res., 12, 367-373 (1996)
  48. Moser G., Status Report on Global Neem Usage. Pesticide Service Project, PN 86.2588.1. GTZ, Griesheim, Germany, 39 (1996)