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Screening of the Cassia fistula Flowers Extract for the Anti-Acne Activity

Author Affiliations

  • 1KMCH College of Pharmacy, Department of Pharmaceutics, Kovai Estate, Kalapatti road, Coimbatore – 641035, Tamil Nadu, INDIA

Res. J. Recent Sci., Volume 1, Issue (11), Pages 53-55, November,2 (2012)

Abstract

Extract of Cassia fistula flowers were screened for their in vitro antimicrobial activity using agar disc diffusion method. The antimicrobial activity of methanolic extract of Cassia fistula flowers were studied against acne causing bacteria, namely Staphylococcus epidermidis. Methanolic extract of Cassia fistula flowers possessed highest antibacterial activity against S. epidermidis. Minimum inhibitory concentration (0.42 mg/mL) and antimicrobial screening (10.01± 0.04 mg/ml) against S. epidermidis were also observed for methanolic extract of Cassia fistula flowers. Phytochemical screening revealed the presence of alkaloids, tannins, saponins, anthraquinones, anthocyanides flavonoids, glycosides and terpenoids which indicates that these phytoconstituents may be responsible for their anti-acne activity.

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