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Synthesis and Biological activity of 4-(3-bromophenyl)-N-(1-(4-(4-bromophenyl) thiazol-2-yl)-3-methyl-4-(2-phenylhydrazono)-4,5-dihydro-1H-pyrazol-5-ylidene)-6-(4-nitrophenyl)pyrimidin-2-amine derivatives

Author Affiliations

  • 1Department of Chemistry, S.I.W.S. College, Wadala, Mumbai- 400 031, Maharashtra, India
  • 2Department of Chemistry, Sant Rawool Maharaj Mahavidyalay, Kudal, Sindhudurg - 416 520, Maharashtra, India
  • 3Department of Chemistry, Kirti College, Dadar, Mumbai-400028, Maharashtra, India

Res.J.chem.sci., Volume 7, Issue (2), Pages 49-53, February,18 (2017)


4-(3-bromophenyl) - N- (1- (4- (4-bromophenyl) thiazol-2-yl)-3-methyl-4-(2-phenylhydrazono)-4,5-dihydro-1H-pyrazol-5-ylidene) -6-(4-nitrophenyl)pyrimidin-2-amine derivatives (3a-h) have been synthesized using conventional method and microwave irradiation. The structure of the synthesized compounds have been confirmed by IR and NMR Spectroscopy. These compounds were evaluated for their biological efficacy.


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