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Go Green with Flavones: Eco-friendly Microwave Assisted Synthesis of some Substituted Flavones

Author Affiliations

  • 1Department of Chemistry, Govt. Polytechnic, Amravati, India
  • 2Department of Chemistry, Brijlal Biyani Science College, Amravati, India

Res.J.chem.sci., Volume 6, Issue (6), Pages 15-18, June,18 (2016)

Abstract

An ecofriendly, economic, easy and greener chemical pathway used to prepare pharmaceutically important substituted flavones on oxidative cyclization of substituted chalcones by microwave irradiation in DMSO/I2 media. Microwave synthesis offers advantages over conventional heating by time, extent of chemicals used and by yield. Flavones synthesized are analyzed by spectra.

References

  1. Naqvi A. and Pandey A. (2015)., Assay method for quality control and stability studies of a new anti-diabetic and anti-dyslipidemic flavones (S002-853)., Pharmacognosy m., 11 (53-59).
  2. M.J. Chan-Bacab and L.M. Petia-Rodriguez (2001)., Flavones as an anti Cancer., Nat. Prod. Prep. 18, 674.
  3. Harborne J.B. (1999)., Flavone: Natural product with pharmaceutical value., Nat. Prod. Rep., 16, 509
  4. Balsubraniyan Kardele. V. (2015)., Flavonoes as antioxidants., Asian J.Chem., 8, 399-406.
  5. Amić D., Davidović-Amić D., Beslo D., Rastija V., Lucić B. and Trinajstić N. (2007)., SAR and QSAR of the antioxidant activity of flavonoids., Curr Med Chem., 14(7), 827-845.
  6. Lokhande D., Sakate S., Taksande N. and Navghare (2005)., Flavones: Anti microbial activity., B. Tetrahedron Lett., 46, 1573.
  7. Kabalka W. and Mereddy R. (2005)., Zaw novel flavonoid compounds., Tetrahedron Lett., 46, 6315.
  8. Li J. and Corey E.J. (2005)., Name Reactions in Heterocyclic Chemistry., John Wiley and Sons, NewYork, 262.
  9. Muthukrishnan M., Patil S., More V. and Joshi A. (2005)., Synthetic approach of flavones., Mendeleev Commun., 15, 100.
  10. Kalai T., Kulcsar G., Osz E., Jeko J., Sumegi B., Hidega K. (2004)., Quinolyl flavones: Medicinal value., ARKIVOC, 7, 266.
  11. Zhou C., Dubrovsky A.V. and Larock R.C. (2006)., Organic letter., J. Org. Chem., 71, 1626.
  12. Pinto J. and Silva V.L. (2015)., Ecofriendly synthesis of heterocycles., Molecules, 20, 11418-11431.