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Synthesis, Characterization and Antimicrobial screening of some Azo compounds derived from Ethyl vanillin

Author Affiliations

  • 1 Department of Chemistry, Vidyabharati Mahavidyalaya, Amravati, 444602, INDIA

Res.J.chem.sci., Volume 5, Issue (7), Pages 20-28, July,18 (2015)


Azo compounds were synthesized in excellent yield by diazotization of some substituted aromatic amines using NaNO2 and concentrated HCl followed by coupling with ethyl vanillin in alkaline medium. These azo compounds were characterized by FTIR and H1 NMR spectroscopic technique and have been tested against the growth of five gram positive and negative microorganisms in order to assess their antimicrobial activity.


  1. Towns A.D., Developments in azo disperse dyes derived from heterocyclic diazo compounds, Dyes and Pigments, 42, 3-28 (1999)
  2. Zollinger H., Synthesis, properties and applications of organic dyes and pigments, Color Chemistry, third revised edition,Wiley-VCH.,Weinheim (2003)
  3. Gayatri C. and Ramalingam A.,Z-scan determination of the third order optical nonlinerities of an azo dye using dipole: pumped Nd:Yag laser, Optik, 119(9), 409-414 (2008)
  4. Sakong C., Kim Y. D., Choi J. H., Yoon C. and Kim J.P., The synthesis of thermally stable red dyes for LCD color filters and analysis of their aggregation and spectral properties, Dyes and Pigments, 88(2),166-173 (2011)
  5. Bae J.S., Freeman H.S. and El-Shafei A., Metallization of non-genotoxic direct dyes, Dyes and Pigments, 57(2), 121-129 (2003)
  6. Sanjay F.T., Dinesh M.P., Manish P.P. and Ranjan G.P., Synthesis and antibacterial activity of novel pyraazolo [3,4-b] quinoline base heterocyclic azo compounds and their dyeing performance, Saudi Pharm. Journal, 15(1), 48-54 (2007)
  7. Child R.G., Wilkinson R.G. and Tomcu-Fucik A., Effect of substrate orientation of adhesion of polymer joints, Chem. Abstr., 87, 6031 (1977)
  8. Garg H.G. and Prakash C.J., Preparation of 4-arylazo-3,5-disubstituted-(2H)-1,2,6-thiadizine1,1-dioxides, Med. Chem.,15(4), 435-436 (1972)
  9. Koshti S.M., Sonar J.P., Sonawane A.E., Pawar Y.A., Nagle P.S., Mahulikar P.P. and More D.H., Synthesis of azo compounds containing thymol moiety, Indian J. Chem., 47B, 329-331 (2008)
  10. Pathan R.U. and Borul S.B., Synthesis and antimicrobial activity of azo compounds containing drug moiety,Oriental J. Chem., 24(3), 1147-1148 (2008)
  11. Rathod K.M., Synthesis and antimicrobial activity of azo compounds containing paracetamol moiety, Oriental J. Chem., 26(3), 1163-1166 (2010)
  12. Rathod K.M. and Thakare N.S., Synthesis and antimicrobial activity of azo compounds containing m-cresol moiety, Chem. Sci.Trans., 2 (1), 25-28 (2013)
  13. Rathod K.M., Synthesis and antimicrobial activity of azo compounds containing resorcinol moiety, Asian J. Research Chem., 4(5), 734-736 (2011)
  14. Pagariya R.F., Rathod K.M. and Thakare N.S., Synthesis, characterization and antibacterial screening of azo compounds containing vanillin moiety, Asian J. Research Chem., 6(9), 824-827 (2013)
  15. Dahake P.R. and Kamble S.I., Investigatory study on antimicrobial activity and phytochemical screening of Butea monosperma Linn, BBRA, 11(3), 1695-1698 (2014)
  16. Alzoreky N.S. and Nakahara K., Antimicrobial activity of extracts from some edible plants commonly consumed in Asia, Int. J. Food Microbial, 80, 223-230 (2003)