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Synthesis, Characterization and Antioxidant studies of Cd(II), Hg(II) and Pb(II) Complexes of some Synthetic curcuminoids

Author Affiliations

  • 1Department of Chemistry, University of Calicut, Thenhipalam, Kerala, INDIA
  • 2PG Department of Chemistry, KAHM Unity Women’s College, Manjeri, Kerala, INDIA

Res.J.chem.sci., Volume 5, Issue (6), Pages 40-45, June,18 (2015)


Cd (II), Hg (II) and Pb (II) complexes of two synthetic curcuminoid analogues derived from pentane-2,4-dione and aromatic aldehydes (furfural and naphthalene-2-carbaldehyde) have been synthesized and characterized by analytical and spectral data. In all the chelates, ligands behaved as monobasic bidentate where the hydrogen bonded enolic proton is substituted by the metal ion. Antioxidant studies of four synthetic curcuminoids (derived from benzaldehyde, cinnamaldehyde, furfural and naphthalene-2-carbaldehyde) revealed that all the ligands possess significant antioxidant activities. Maximum activity was observed with 2-naphthyl curcumin. Metal complexation enhanced the antioxidant activity of all the compounds and among these Hg(II) complexes showed highest activity.


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