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A Novel Kinetic Assay for the Examination of Solid-Liquid Extraction of Flavonoids from Plant Material

Author Affiliations

  • 1School of Environment, University of the Aegean, Mitr. Ioakim Street, Myrina, 81400, Lemnos, GREECE

Res.J.chem.sci., Volume 5, Issue (11), Pages 18-23, November,18 (2015)


The medicinal plant Artemisia inculta, endemic to the island of Crete (southern Greece), was chosen as a matrix for the examination of solid-liquid extraction of total flavonoids, using a novel kinetic model based on a rectangular 2-parameter hyberbola function, which was established employing non-linear regression. The determination of basic kinetic parameters and the critical comparison with the well-studied and widely used second-order model, proved unequivocally that the model proposed can be implemented as an alternative means of describing solid-liquid extraction kinetics, with high reliability. The advantage over other models used in similar processes is the simplicity of the determination of the basic kinetic parameters, by utilising a “double reciprocal” linear mathematical transformation


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