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Synthesis Characterization and Fungicidal activity of 2- Amino -4- (P- Ethoxy Phenyl) Oxazole Complexes of Transition Metal (II) ions

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Author Affiliations

  • 1Department of Chemistry, MS College, Saharanpur, UP, INDIA
  • 2Department of Botany, MS College, Saharanpur, UP, INDIA

Res.J.chem.sci., Volume 4, Issue (5), Pages 48-51, May,18 (2014)

Abstract

Transition metal (II) complexes of the ligand 2-amino-4-(p-ethoxy phenyl) oxazole (C11H12N2O2) have been prepared. The complex is of the type (M2L2X2) where M= Cu, Co and Ni. The infrared studies suggest that 2-amino-4-(p-ethoxy phenyl) oxazole behaves as a bidentate ligand with nitrogen of amino group and oxygen of oxazole ring as two co-ordination sites. The structure of complexes was characterized with the help of their elemental analysis, IR, electronic and magnetic susceptibility studies. The magnetic and electronic spectral studies indicate an octahedral geometry for the complexes with the (M2L2X2) formula. These newly synthesized complexes were also screened for their antifungal activity against different fungi at different concentrations. The activity decreases with decrease of concentration and the metal complexes are less toxic than the parent ligand.

References

  1. Bharti S.K., Nath G., Tilak R. and Singh S.K., Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2,4-disubstituted thiazole ring, Eur J Med Chem.,(45), 651-660 (2010)
  2. Singh W.M. and Dash B.C. Synthesis of some new schiff bases containing thiazole and oxazole nuclei and their fungicidal activity, Pesticides, (22), 33 (1988)
  3. Khamamkar Ashwini and Pallapothula Rao Venkateshwar., Synthesis, Spectral Characterization and Biological activity of Schiff’s base derived metal complexes, J. Ind. Council Chem., 29(1&2),71-76 (2012)
  4. Reddy V., Patil N. and Angadi S.D., Synthesis, Characterization and Antimicrobial Activity of Cu(II),Co(II) and Ni(II) Complexes with O, N, and S Donor Ligands, E-J. Chem., 5(3), 577-583 (2008)
  5. Chandra S. and Sangeetika J., EPR and electronic spectral studies on copper(II) complexes of some N-O donor ligands, J. Indian Chem. Soc., (81), 203 (2004)
  6. Pandeya S.N. Sriram D. Nath G. and Clercq E. de., Synthesis, antibacterial, antifungal and anti- HIV evaluation of Schiff and Mannich bases of isatin and its derivatives with triazole, Arzneimittel Forsch., (50), 55 (2000)
  7. Shriodkar S.G. Mane P.S. and Chondhekar T.K. Synthesis and fungitoxic studies of Mn(II), Co(II), Ni(II) and Cu(II) with some heterocyclic Schiff base ligands, Indian J. Chem,(40A), 1114-1117 (2001)
  8. Ravanasiddappa M. Sureshg T. Syed K. Radhavendray S. C. Basavaraja C. and Angadi S. D., Transition Metal Complexes of1, 4(2'-Ethoxyphenyl-1-yl) di-iminoazine: Synthesis, Characterization and Antimicrobial Studies, E-J. Chem., 5(2), 395-403 (2008)
  9. Belaid S. Landreau A. Benali-Baitich O. Khan M.A. and Bouet G., Synthesis, characterisation and antifungal activity of a series of cobalt(II) and nickel(II) complexes with ligands derived from reduced N, N'-ophenylenebis (salicylideneimine), Trans. Met. Chem., (33), 511 (2008)
  10. Mapari A.K. and Mangaonkar K.V. Synthesis, Characterization and Antimicrobial Activity of Mixed Ligand Complexes of N-(2-ethoxy-1-naphthylidene)-2,6-diisopropylaniline and N-(2-ethoxybenzylidene)-2,3-dimethylaniline with Co(II), Ni(II), Cu(II) and Zn(II) ions, International Journal of ChemTech Research, 3(2), 636-641(2011)
  11. Mane P.S. Shirodkar S.G. Arbad B.R. and Chondhekar., T.K. I. JC, Sec A; Inorganic, Bio-inorganic, Physical & Analytical Chemistry., 40A(6), 648 (2001)
  12. Manch W. and Conard Fernelius W., The Structure and Spectra of Nickel(II) and Copper(II) Complexes, Journal of Chemical Education., 38 (4), 192-201 (1961)
  13. Naik B. and Desai K., Novel approach for the rapid and efficient synthesis of heterocyclic Schiff bases and azetidinones under microwave irradiation, Indian journal of chemistry., (45B), 267-271 (2006)
  14. Soliman A.A., El-Medani S.M. and Ali O.A.M. journal of thermal analysis and calorimetry, thermal study of chromium and molybdenum complexes with some nitrogen and nitrogen–oxygen donors ligands 83(2), 385-392(2006 )
  15. Vogal A.I., A Text Book of Quantitative Inorganic Analysis. 3rd ed. (English Language Book Society and Longman)., (1961)
  16. Vogal A.I., Quantitative Organic Analysis., (1958)
  17. Dodson R.M. and King L.C., The reaction of ketones with halogens and thiourea, J. Am. Chem. Soc.,(67), 2242(1945)
  18. Nakamato K., Infrared Spectra of inorganic and coordination Compounds, John Wiley, New York, (1970)
  19. Nakamoto K., Infrared and Raman Spectra of Inorganic and Coordination Compounds, New York: Wiley, (1978)
  20. Liver A.B.P., Inorganic electronic spectroscopy. Elsevier, New York, (1984)
  21. Figgis B.N. and Lewis J., Prog. Inorg. Chem., (6),37(1965)
  22. Earnshaw A. Introduction to Magnetochemistry, Academic Press, New York, (1968)