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Diverse Pharmacological aspects of Benzimidazole Derivatives: A Review

Author Affiliations

  • 1 Dept. of Chemistry & Post Graduate Research Centre, Abeda Inamdar Sr. College of Arts, Science & Commerce, Camp, Pune – 411001, INDIA

Res.J.chem.sci., Volume 4, Issue (4), Pages 78-88, April,18 (2014)

Abstract

Benzimidazole is the heterocyclic compound formed by the fusion of benzene and imidazole ring. Benzimidazole analogs are of great significant because of their various clinical applications and biological activity. Benzimidazoles are considered as an optimistic class of bioactive heterocyclic compounds that possesses a range of biological activities. The work in this article relates to benzimidazole as it is a versatile heterocycle possessing a wide spectrum of biological activities like antimicrobial, antiviral, antidiabetic, anticancer activity, numerous antioxidant, antiparasitic, antihelmintics, antiproliferative, antiHIV, anticonvulsant, anti-inflammatory, antihypertensive, antineoplastic, proton pump inhibitor and antitrichinellosis. Benzimidazoles possess significant biological activities likepotential antitumor agents, smooth muscle cell proliferation inhibitors and in various areas of chemistry.

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