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Phytochemical and Pharmacognostic Analysis of Alstonia Scholaris (l) R. BR., A commonly available Medicinal Plant in Assam, India

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Author Affiliations

  • 1Department of Chemistry, Gauhati University, Guwahati, 781014, Assam, INDIA
  • 2Brahmaputra Valley Academy, North Lakhimpur-787001, Assam, INDIA

Res.J.chem.sci., Volume 4, Issue (11), Pages 68-71, November,18 (2014)

Abstract

Phytochemical analysis of methanolic extracts of leaf, bark and latex of Alstonia scholaris (L) R.Br. revealed marked variation in overall content of phenolics in leaf, bark and latex extracts. The leaf extract had highest content of overall phenolics followed by bark and latex extracts. In the leaf extract, flavonoids and proanthocyanidins were present in abundance with values observed 89 mgQE/g DW and 92 mgCE/g DW, respectively, whereas the phenolics were only 49 mgGAE/gDW. In the bark extract, level of flavonoids and phenolics were comparatively lower than leaf extract, however proanthocynidins (66 mgCE/g DW) was found significantly higher. Latext extract had lowest content of phenolics (26 mgGAE/g DW), flavonoids (16 mgQE/g DW) and proanthocynidins (21mgCE/g DW). Methanol extracts of A. scholaris leaves, bark and latex extracts exhibited strong antioxidant activities in terms of scavenging DPPH free radicals. Antimicrobial microbial rtesponse have been observed.

References

  1. Phytochemical Analysis and Anti Microbial Activity of Mimosa pudica Linn.,Tamilarasi T. and Ananthi T., Res. J. chem. sci.,2(2), 72-74 (2012)
  2. Mukherjee P.K. and Wahile A., Integrated approaches towards drug development from Ayurveda and other Indian system of medicines, J Ethnopharmacol.,103, 25-35 (2006)
  3. Antibacterial Potential of Achyranthus aspera Linn Procured from Himachal Pradesh, Punjab and Haryana, India, Sharma Raj Neeta, Bala Jyoti, Singh Anjuvan and Kaur Prabhjot, Res.J.chem.sci.,1(8), 76-79 (2011)
  4. Nataraj, H.R. and Hiremath S.K., Pharmacognostic and phytochemical analysis of different market samples of Asoka (Saraca indica Linn.), Ancient Science of Life,29(2), 7-11 (2009)
  5. Liu X., Zhao M., Wang J., Yang B. and Jiang Y., Antioxidant activity of methanolic extract of emblica fruit (Phyllanthus emblica L.) from six regions in China, J. Food Compos. Anal., 21(3), 219–228 (2008)
  6. Jia Z., Tang M., and Wu J., The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals, Food Chem., 64(4), 555–559 (1999)
  7. Manikandan S., and Devi R.S., Antioxidant property of alpha-asarone against noise-stress-induced changes in different regions of rat brain, Pharmacol Res., 52(6), 467–7 (2005)
  8. Arulmozhi S, Mazumder P.M, Narayanan L.S, Thakurdesai P.A., In vitro antioxidant and free radical scavenging activity of fractions from Alstonia scholarisLinn.R.Br., Int. J. Pharm. Tech. Res., 18–25 (2012)
  9. Enrichment of Flavonoids from the Methanolic Extract of Boerhaavia Diffusa Roots by Partitioning Technique, Mahesh A.R., Ranganath M.K. and Harish Kumar D.R., Res. J. Chem. Sci., 3(1),43-47(2013)
  10. Kumar A, Kaur R. and Arora S., Free radical scavenging potential of some Indian medicinal plants., J. Med. Plant Res., 4(19), 2034–2042 (2010)
  11. Preliminary Phytochemical Analysis of some Plant Seeds, Ajayi I.A., Ajibade O. and Oderinde R.A., Res.J.chem.sci., 1(3), 58-62 (2011)
  12. Kulkarni P.M., and Juvekar A.P., Effect of Alstonia scholaris R.Br. on stress and cognition in mice, Indian J. Exp. Biol., 47(1), 47– 50 (2008)
  13. Proximate and Phytochemical Analyses of Solanum aethiopicum L. and Solanum macrocarpon L. Fruits Shalom Nwodo Chinedu, Abayomi C. Olasumbo, Okwuchukwu K. Eboji, Opeyemi C. Emiloju, Olajumoke K. Arinola and Damilola I. Dania, Res.J.chem.sci.,1(3),63-71(2011)
  14. Sim K.S., Nurestri A.M. and Norhanom A.W., Phenolic content and antioxidant activity of Pereskia grandifoliaHaw.(Cactaceae) extracts., Pharmacogn. Mag., 6(23),248–5 (2010)
  15. Kumar V, Gogoi B.J., Meghvansi M.K., Singh L, Srivastava R.B. and Deka D.C., Determining the antioxidant activity of certain medicinal plants of Sonitpur, (Assam), India using DPPH assay., J. Phytol., 1(1), 49–56 (2009)
  16. Pankti K., Payal G., Manodeep C. and Jagadish K. A., phytopharmocological review of Alstonia scholaris: A panoramic herbal medicine, Int. J. Res. Ayu. Pharm., 3(3), 367–371 (2012)
  17. James J, Veettil A.K.T., Pratyush K, Misra CS, Sahadevan L.D.M. and Thankamani V., In vitro antioxidant activity of flowers and fruits of Alstonia scholaris. Int. J. Phytomed., 3(4), 475–479 (2011)