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Synthesis and Biological Activities of Selected Quinolone-Metal Complexes

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Author Affiliations

  • 1Department of Applied Chemistry and Polymer Technology, Delhi Technological University, Delhi – 110 042, INDIA
  • 2 Department of Chemistry, University of Delhi, Delhi-110007, INDIA

Res.J.chem.sci., Volume 3, Issue (6), Pages 83-94, June,18 (2013)

Abstract

4-Quinolones are the synthetic antibacterial agent structurally related to nalidixic acid. The coordination chemistry of these drugs with metal ions of biological and pharmaceutical importance is an active research area. In this review article, synthesis and biological activity of metal complexes of selected 4-quinolones such as norfloxacin, ciprofloxacin, enrofloxacin, gatifloxacin, and sparfloxacin are presented and discussed.

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