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Synthesis Characterization and Antimicrobial studies of some Novel Sulphonamides containing Substituted Naphthofuroyl group

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Author Affiliations

  • 1Department of Chemistry, University College of Science, Tumkur University, B.H. Road, Tumkur-572 103, Karnataka, INDIA
  • 2Department of Chemistry, Kuvempu University, Shankaraghatta, Shimoga, Karnataka, INDIA

Res.J.chem.sci., Volume 3, Issue (1), Pages 15-20, January,18 (2013)

Abstract

Prompted by the varied biological activities of sulphonamides, and Naphthfurans, a series of sulphonamides (5a-f) derived from naphthofurans were prepare by treating sulphonamides (4a-b) with naphofuroic acids (3a-c) employing POCl heating for 1hr. at 60-70C. The structures of these novel compound were comfirmed on the basis of elemental analysis and spectral data. All the title compound were screened for their antimicrobial activites. The screening data indicated that testing compound were found be less active than the standard drug.

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