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The Benefits of using an Intravenous Infusion of Mixture of Soluble Insulin in 50% Dextrose in Controlling Diabetic Patient\'s Blood Sugar During Open Heart Surgery

Author Affiliations

  • 1College of Medicine, Hawler Medical University. Cardiac Anesthesia, Erbil Cardiac Center, Erbil, Kurdistan, Iraq
  • 2Erbil Cardiac Center / Erbil / Kurdistan / Iraq

Int. Res. J. Medical Sci., Volume 4, Issue (8), Pages 12-17, August,28 (2016)


The main aim of this study is to compare the effect of the mixture of soluble insulin in 50% dextrose and the effect of mixture of the soluble insulin in 0.9% saline in controlling blood sugar of diabetic patients during open heart surgery. Fifty adult patients aged 45-75 years, Anesthesiologists physical status class 3 and 4 scheduled for open heart surgery operations were clinically randomized to receive either 50 IU soluble insulin in 0.9% saline (group A, n=25) according to their blood glucose level or 50 IU soluble insulin in 50% dextrose (group B, n=25) 0.1ml/kg/hr. The comparison between the two groups was based on four blood samples had been taken before induction of anesthesia, after induction, 30 minutes from establishing the full rate of bypass machine, and 30 minutes from off bypass. These results indicated that using a mixture of soluble insulin in 50% glucose water shows a positive effect in controlling blood sugar than in 0.9% saline in four blood sampling. The most significant result was the third sample which was 30 minutes from establishing the full rate of bypass machine.


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