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Predictive value of basal FSH, Endometrial thickness, Pattern and Serum E2 in In-vitro Fertilization embryo transfer cycles success

Author Affiliations

  • 1 Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, INDIA

Int. Res. J. Medical Sci., Volume 2, Issue (7), Pages 6-11, July,28 (2014)

Abstract

To evaluate predictive value of basal FSH, serum estradiol (E) and endometrial thickness and pattern in success of IVF-ET (In vitro fertilization- embryo transfer) cycles. A total of 211 patients under went long protocol which started in secretory phase (day 21) of cycle and success rate of IVF-ET cycle is determined on the basis of clinical pregnancy rate (CPR). All the patients were studied on the various parameters like age, type of infertility, cause of infertility, basal FSH, serum estradiol, endometrial thickness and pattern on the day of HCG injection, number of ampoules of Gonadotrophins used, no. of follicles, oocyte retrieved, embryo formed, embryo grade. Predictive value of basal FSH, serum estradiol and endometrial thickness and pattern were assessed in success of IVF-ET cycles. Success rate in present study is 37.44%. Overall mean age of study group is 32.49+_3.42 years. This study indicates that significant predictive factors are basal FSH, endometrial thickness, presence of triple line, peak estradiol level, and age, number of follicle, oocyte, and embryo formed and transferred has effect on CPR. Embryo grade is independent predictor of IVF success. Basal FSH is a marker of ovarian reserve and value &

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