International E-publication: Publish Projects, Dissertation, Theses, Books, Souvenir, Conference Proceeding with ISBN.  International E-Bulletin: Information/News regarding: Academics and Research

Etiology and Drug Resistance Profile of Pediatric Urinary Tract Infections in Eastern India

    , ,

Author Affiliations

  • 1Dept. of Microbiology, B.U, Burdwan, INDIA
  • 2 KIEM, Mankar, Burdwan, INDIA
  • 3 Dept. of Microbiology, BMCH, Burdwan, INDIA

Int. Res. J. Medical Sci., Volume 2, Issue (6), Pages 11-13, June,28 (2014)

Abstract

The present study had been conducted to provide information on the spectrum of bacteria involved in pediatric UTI in Eastern India and their drug sensitivity pattern. Drug susceptibility testing of the isolates were done and the results were interpreted following the Clinical and Laboratory Standards Institute guidelines. The overall prevalence of UTI was found to be 196/300 (65.3%). Escherichia coli was the dominant urinart tract pathogen in our pediatric population, this being followed by Proteus spp. and Klebsiella sp. E. coli displayed high level of resistance against tetracycline and ampicillin. Parenteral antibacterials, like gentamicin, amikacin and nitrofurantoin were found to be effective against urinary tract pathogens.

References

  1. Chomarat M., Resistance of bacteria in urinary tract infections, Int.J of antimicro. Agen., 16, 483-7 (2000)
  2. Gupta K., Emerging antibiotic resistance in urinary tract infections, Inf. Dis. Clin. of North America., 17, 243–59 (2003)
  3. Prais D et al., Bacterial susceptibility to oral antibiotics in community acquired urinary tract infections, Arch. of dis. in childhood, 88, 215–8 (2003)
  4. Sefton A. M., The impact of resistance on the management of urinary tract infection, Int. J of antimicro. Agen., 16, 489–91 (2000)
  5. Prakash D. and Saxena R. S., Distribution and Antimicrobial Susceptibility Pattern of Bacterial Pathogens Causing Urinary Tract Infection in Urban Community of Meerut City, India, ISRN Microbiol., 1-13 (2013)
  6. Elpis M., et al., Antimicrobial susceptibility of pediatric uropathogens in Thrace, Greece, Int. Urol. Nephrol., 43,549–55 (2011)
  7. Gruneberg G. N., Antibiotic sensitivities of urinary pathogens, 1971-1982, J Antimicrob Chemothr.,14, 17-23 (1984)
  8. Biswas D. and et al., Choice of antibiotic for empirical therapy of acute cystitis in a setting of high antimicrobial resistance, Ind. J. of Med. Sci., 60(2), 53–58 (2006)
  9. Akram M., Shahid M, and Khan A. U., Etiology and antibiotic resistance patterns of community-acquired urinary tract infections in J N M C Hospital Aligarh, India, Ann. of Cli. Microbiol. and Antimicr., 6(4), (2007)
  10. Kothari A. and Sagar V., Antibiotic resistance in pathogens causing community-acquired urinary tract infections in India: a multicenter study, The J of Inf. in Dev. Coun., 2 (5),354–58 ( 2008)
  11. Azra S. H., Nair D., Kaur J., Baweja G., Deb M., Aggarwal P., Resistance patterns of urinary isolates in a tertiary Indian hospital, J Ayub Med CollAbottabad., 19, 39-41 (2007)
  12. Kirby W. M., Bauer A. W. and et al., Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol., 45, 493–96 (1966)
  13. Clinical Laboratories Standards Institute (CLSI). Performance of standards for antimicrobial disk susceptibility tests; approved standards, 10th ed. M02- A10. Vol 29. Wayne, PA: CLSI; (2009)
  14. Nys S. et al., Urinary tract infections in general practice patients: diagnostic tests versus bacteriological culture, J. of Antimicro.Chemo.,57( 5), 955–58 (2006)
  15. Nys S. et al., Antibiotic treatment and resistance of unselected uropathogens in the elderly, Int.J of Antimicro. Agen.,27( 3), 236–41 (2006)
  16. Adjei O. and Opoku C., Urinary tract infections in African infants, Int. J. Antimicrob. Agen., 24, 32–4 (2004)
  17. Allen U., MacDonald N. and Fuite L., Risk factors for resistance to first-line antimicrobials among urinary tract isolates of Escherichia coli in children, CMAJ, 160, 1436–40 (1999)
  18. Haller M., Brandis M. and Berner R., Antibiotic resistance of urinary tract pathogens and rationale for empirical intravenous therapy, Pediatr. Nephrol.,19, 982-6 (2004)
  19. Prais D. et al. Bacterial susceptibility to oral antibiotics in community acquired urinary tract infection, Arch. Dis. Child.,88, 215–18 (2003)