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An interventional trial to evaluate efficacy of Nutool Therapy in control of Primary insomnia among elderly using Structured Insomnia schedule

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Author Affiliations

  • 1Dept. of Tahaffuzi wa Samaji Tibb, HMS Unani Medical College, Tumkur, INDIA
  • 2 Dept. of Tahaffuzi wa Samaji Tibb, NIUM, INDIA
  • 3 Dept. of Ilmul Advia, HMS Unani Medical College, Tumkur, INDIA
  • 4 National Institute of Unani Medicine, Bangalore, INDIA
  • 5Dept. of Ilaj Bit Tadbeer, INDIA
  • 6 Dept. of Ilmul Advia, NIUM,

Int. Res. J. Medical Sci., Volume 2, Issue (2), Pages 1-6, February,28 (2014)

Abstract

Insomnia is a unique and complex problem in geriatric population. As many as half of the elderly population between 60 to 79 years of age complain of disturbed sleep, which includes increased sleep latency, decreased quality of sleep, awaking symptoms, excessive daytime sleepiness, mental stress/ depression which may result in disturbed intellect, impaired cognition, confusion, psychomotor retardation the whole syndrome of complaints can compromise patient’s quality of life and create social and economic burden for caregiver. Considering the wide spread prevalence of insomnia in geriatrics, compounded with lack of wholesome drugs in the treatment, an interventional study was carried out with the objectives to evaluate the efficacy and safety of Nutool therapy in control of geriatric insomnia. A total of 30 elderly primary insomniacs,diagnosed for primary insomnia by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition,were randomly assigned to test and control groups, comprising 15 patients in each group, respectively. In the test group, Nutool was performed with Roghan e Banafsha (500ml) and Roghan e Gul (500ml), both mixed in equal ratio while Nutool was done with liquid paraffin in control group. The therapy was scheduled on alternate days for one month. Various insomnia related parameters was evaluated by Structured Insomnia schedule. Statistical analysis was done using student t-test (paired) for comparison in intra group and t-test (unpaired) for inter-group comparison. Nutool therapy showed statistically significant improvement in all the parameters of Structured Insomnia schedule, when pre and post interventional values of the parameters were assessed in intra as well as inter group comparisons. This intervention proves the efficacy and safety of Nutool therapy in control of insomnia among elderly.

References

  1. Roth T., Hajak G. and Ustun T.B., Consensus for the pharmacological management of insomnia in the new millennium, Int J Clin Practic, 55(1), 42-52 (2001)
  2. Belanger L., Belleville G. and Morin M.C., Management of hypnotic dyscontinuation in chronic insomnia, Sleep Med Clin,, 583-592 (2009)
  3. Breslau N., Roth T., Rosenthal L. et al., Sleep disturbances and psychiatric disorders: a longitudinal epidemiological study in young adults, Biol psychiatry, 39(6), 411-8 (1996)
  4. Terzano M.G., Parrino L., Bonanni E., Crignotta F., Ferrillo F. and Gigli G.L. et al., Insomnia in general practice –a consensus report produced by sleep specialist and primary-care physicians in Italy, Clin Drug Invest, 25(12), 745-764 (2005)
  5. Insomnia newer hypnotic drugs, http://www.nice.org.ku/guidance/index.jsp?action=byID&o=11530. cited on 3-4- 2010 (2010)
  6. Krishnan P. and Hawranik P., Diagnosis and management of geriatric insomnia: A guide for nurse practitioners, Journal of the American Academy of Nurse Practitioners, 20(12), 590 (2008)
  7. Ibn sena, kulliyat e qanoon, (Urdu translation by Kabir uddin.), vol 1,2 New Delhi: Eijaz Publication House, 156-156 (2003)
  8. Ibn Sina, Al Qanoon Fil Tib (urdu translation by Kantoori GH), vol I. New Delhi: Idarae Kitabul shifa, 20 (2007)
  9. 9.Erman M., Polysomnographic and patient reported evaluation of the efficacy and safety of eszopiclone in elderly subjects with chronic insomnia, Sleep, 27(Suppl), 257-258 (2004)
  10. Scarf M. A 2 week efficacy and safety of eszopiclone in elderly patients with primary insomnia, Sleep, 28, 720-727 (2005)
  11. Stephen Feren, Anup Katyal. Efficacy of Hypnotic Medications and Other Medications Used for Insomnia, Sleep Medicine Clinics, 1(3), 387-397 (2006)
  12. Philips S Wang, Effects of Hazardous benzodiazepines regimens in the elderly: The American Journal of psychiatry, 158(2), 156, 158, 892, 897 (2001)
  13. Morin C.M., Culbert J.P. and Schwartz S.M., Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy, Am J Psychiatry,151(8), 1172–1180 (1994)
  14. Krystal J.K., Sustain efficacy of eszopiclone over six month of nightly treatment: results of a randomized, double-blind, placebo- controlled study in adult with chronic insomnia, Sleep, 26, 793-799 (2003)
  15. W. Vaughn McCall, Erman M.A., polysomnographic study of eszopiclone in elderly patients with insomnia, Current Medical Research and Opinion, Newbury: Sleep, 22(9), 1633 (2006)
  16. Stephen Feren, Anup Katyal, Efficacy of Hypnotic Medications and Other Medications Used for Insomnia, Sleep Medicine Clinics, 1(3), 387-397 (2006)