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Neonatal Sepsis; The Bacterial Causes and the Risk Factors

Author Affiliations

  • 1 Department of microbiology, College of Medicine, University of Babylon, Hilla, IRAQ

Int. Res. J. Medical Sci., Volume 1, Issue (6), Pages 19-22, July,28 (2013)

Abstract

This study aimed in part to detect the bacterial types implicate in neonatal sepsis with determining the risk factors enable organisms to access neonates. The subjects of the study comprised 50 neonates who admitted to the Preterm Unit and Intensive Care Unit (ICU) in the Babylon Hospital for Pediatric and Gynecology during a period of 6 months (from October 2011 to March 2012). The neonates included both sexes, males and females whose ages ranged from 1 to 90 days. Historical data were fully recorded for each newborn. After clinically investigation and, blood samples were collected and tested for WBCs count and C-reactive protein (CRP) as preliminary indicative tests for infection. Then, a blood samples was cultured on blood agar, MacConkey agar, and nutrientagar media to identify the bacterial types causing the infection. The results indicated that Early Onset Sepsis (EOS) is more frequent than Late Onset Sepsis ( LOS) and Gram negative bacteria were found to be the common causes sepsis of neonates sepsis. The results showed that abnormal WBCs count and positive CRP were significantly associated with blood culture proven septicemia.

References

  1. Shahsanam G., Zahra F., Mohammad K., Javad K., Behrooz I., Farzin A., Hashem M. and Amir H., M. Coagulase negative staphylococcus; the most common cause of neonatal septicemia in Urmia, Iran, Iran J. Pediatr. 18, 237-243 (2008)
  2. Movahedian A.H., Moniri R. and Mosayebi Z., Bacterial culture of neonatal sepsis, Iranian J. Publ. Health, 35, 84-89 (2006)
  3. World Health Organization, Perinatal mortality, Report No: FRH / MSM/967, Geneva (1996)
  4. Jumah D.S. and Hassan M.K., Predictors of mortality outcome in neonatal sepsis, Med. J. Basrah Uni., 25, 11-18 (2007)
  5. Costello A., Francis V., Byrne A. and Puddephatt C., State of the world's newborns: a report from Saving Newborn Lives, Washington DC: Save the Children and Women and Children First (2001)
  6. Vergnano S., Sharland M., Kazembe P., Mwansambo C. and Heath P.T., Neonatal sepsis: an international perspective, Arch. Dis. Child. Fetal Neonatal Ed., 90, 220-224 (2005)
  7. Heath P.T., Nik Y. and Baker C., Neonatal meningitis, Arch Dis Child Fetal Neonatal Ed., 88, F173–178, (2003)
  8. Motara F., Ballot D.E. and Perovic O., Epidemiology of neonatal Sepsis at Johannesburg Hospital, Southern Afr. J. Epidemiol. Infect., 20, 90-93 (2005)
  9. Edwards M.S., Postnatal infections. In: Neonatal‐Perinatal Medicine, Edited by Fanaroff, Martins, 8th ed. Philadelphia, Mosby Elsevier; 791‐804 (2006)
  10. Tallur S.S., Kasturi A.V., Nadgir S.D. and Krishna B.V., Clinico-bacteriological study of neonatal septicemia in Hubli, Indian J Pediatr., 67, 169–74 (2000)
  11. Gotoff S.P., Infections of the neonatal infants, In: Nelson Textbook of Pediatrics, 15th, Ed. Eds.; Nelson, W.E., Behram, P.E., Kliegman, R.M., Arvin, A.M., Saunders, Philadelphia, USA, 514-540 (1996)
  12. Blanc W.A., Pathways of fetal and early neonatal infection, J. Pediatr., 59, 473-49(1961)
  13. Wilson H.D. and Eichenwald H.F., Sepsis neonatorum, Pediatr. Clin. North. Am., 21, 571-582 (1974)
  14. Weinschenk N.P., Farina A. and Bianchi D.W., Premature infants respond to early-onset and late-onset sepsis with leukocyte activation, J. Pediatr., 137, 345-350 (2000)
  15. MacFaddin J.F., Biochemical tests for identification of medical bacteria, 3rd.edn. Williams and Wilkins- Baltimor, USA (2000)
  16. Chetana Vaishnavi, Immunology and Infectious Diseases, 6, 139-144 (1996)
  17. Rasul C.H., Hassan M.A. and Habibullah M., Neonatal sepsis and use of antibiotic in tertiary care hospital, Pak J Med Sci., 23, 78-81 (2007)
  18. Dawodu A., al Umran K. and Twum-Danso K., A case control study of neonatal sepsis: Experience from Saudi Arabia, J. Trop. Pediatr. 43, 84-88 (1997)
  19. Aftab R. and Iqbal I., Bacteriological agents of neonatal sepsis in NICU at Nishtar Hospital Multan, J.C.P.S., 16, 216-9 (2006)
  20. Misallati A., el-Bargathy, S. and Shembesh, N. Blood-culture-proven neonatal septicemia: a review of 36 cases. East Mediterr. Health J. 6, 483-6 (2000)