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Evaluation of Anti-ulcer activity of hydro alcoholic extract of Post Sumaq (Rhus coriaria Linn.) in Ethanol induced Gastric ulcer in experimental Rats

Author Affiliations

  • 1Dept of Ilmul Advia (Pharmacology), National Institute of Unani medicine, Bangalore-91, Karnataka, INDIA

Int. Res. J. Medical Sci., Volume 1, Issue (10), Pages 7-12, November,28 (2013)

Abstract

The anti-ulcer activity of hydro alcoholic extract of Rhus coriaria Linn. was investigated in ethanol induced gastric ulcer in Wistar rats. The assessment was carried out by using ulcer index, ulcer score and histopathological studies of the specimens. The extract at doses of 145 and 248 mg/kg given orally produced significant inhibition of the gastric lesions induced by ethanol as compared to control groups and the results were comparable to the standard treatment regime. Present study indicated that Rhus coriaria Linn extract has substantial anti ulcer activity in experimental rats, thus it may favour the Unani claims about effectiveness of this drug in case of gastric ulcer disease.

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