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Evaluation of antioxidant activity of crude extracts and different fractions of stem bark of Acacia nilotica

Author Affiliations

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
  • 2Department of Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
  • 3Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
  • 4Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh

Res. J. of Pharmaceutical Sci., Volume 6, Issue (5), Pages 1-16, July,30 (2017)

Abstract

Antioxidants may be defined as radical scavengers which protect the human body against free radicals that may cause pathological conditions such as ischemia, anemia, asthma, arthritis, inflammation, neurodegeneration, Parkinson\'s diseases, mongolism, ageing process and perhaps dementias. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. Dichloromethane fraction and methanolic extract of bark of Acacia nilotica showed moderate antioxidant activity with the IC50 values 157.41 &

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