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Isolation and Structural Characterization of Lupane Triterpenes from Polypodium Vulgare

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Author Affiliations

  • 1The Coca-Cola Company, Organic Chemistry Dept, Global Research and Development, One Coca-Cola Plaza, Atlanta, GA, USA

Res. J. of Pharmaceutical Sci., Volume 1, Issue (1), Pages 23-27, September,30 (2012)

Abstract

Purification of the dichloromethane (CH2Cl2) fraction of the aqueous alcoholic extract of the rhizomes of polypodium vulgare resulted in the isolation of three lupane triterpenes namely lupenone, lupeol, and betulinic acid. The structures of isolated compounds were characterized on the basis of extensive spectral data (1D and 2D NMR; and MS) and in comparison with their physical and spectral data reported earlier.

References

  1. Berti G., Bottari F., Marselli A., Morelli I. and Mandelbaum A., Isolation of serratene from Polypodium vulgare, J. Chem. Soc., Chem. Commun., 507 (1967)
  2. Berti G., Bottari F., Macchia B., Mardili A., Ourisson G. and Piotrowska H., Cyclolanostanic triterpenes isolated from ferns, Bull. Soc. Chim. Fr., 2359 (1967)
  3. Heinrich G. and Hoffmeister H., 5-Hydroxyecdysterone, a plant steroid with growth and differentiation hormone activity from Polypodium vulgare, Tetrahedron Lett.,6063 (1968)
  4. Yamada H., Nishizawa M. and Katayama C., Osladin, a sweet principle of Polypodium vulgare. Structure revision, Tetrahedron Lett.,33, 4009-10 (1992)
  5. Chaturvedula V.S.P., Mani U. and Prakash I., Diterpene glycosides from Stevia rebaudiana, Molecules, 16, 3552-3562 (2011)
  6. Chaturvedula V.S.P. and Prakash I., A new diterpenoid glycoside from Stevia rebaudiana, Molecules, 16, 2937-2943 (2011)
  7. Chaturvedula V.S.P. and Prakash I., Structures of the novel diterpene glycosides from Stevia rebaudiana, Carbohydr. Res.346, 1057-1060 (2011)
  8. Chaturvedula V.S.P., Rhea J., Milanowski D., Mocek U. and Prakash I., Two minor diterpene glycosides from the leaves of Stevia rebaudiana, Nat. Prod. Commun., 175-178 (2011)
  9. Chaturvedula V.S.P., Clos J.F., Rhea J., Milanowski D., Mocek U., DuBois G.E. and Prakash I., Minor diterpene glycosides from the leaves of Stevia rebaudiana, Phytochem. Lett., 209-212 (2011)
  10. Chaturvedula V.S.P. and Prakash I., Additional minor diterpene glycosides from Stevia rebaudiana, Nat. Prod. Commun., 1059-1062 (2011)
  11. Chaturvedula V.S.P., Mani U. and Prakash I., Structures of the novel -glucosyl linked diterpene glycosides from Stevia rebaudiana, Carbohydr. Res.346, 2034-2038 (2011)
  12. Chaturvedula V.S.P., and Prakash I., Cucurbitane glycosides from Sitaitia grosvenorii, J. Carbohydr. Chem..30, 16-26 (2011)
  13. Jamal A.K., Yacoob W.A. and Din L.B., A Chemical study on Phyllanthus columnaris, Eur. J. Scien. Res., 28, 76-81 (2009)
  14. Baek M.-Y., Cho J.-G., Lee D.-Y., Ahn E.-M., Jeong T.-S. and Baek N.-I., Isolation of triterpenoids from the stem bark of Albizia julibrissin and their inhibition activity on ACAT-1 and ACAT-2, J. Korean Soc. Appl. Biol. Chem., 53, 310-315 (2010)
  15. Rajavel R., Mallika P., Rajesh V., Pavan Kumar K., Krishna Moorthy S. and Sivakumar T., Antinociceptive and antiinflammatory effects of the methanolic extract of Oscillatoria annae, Res. J. Chem. Sci.,2(7)53-61 (2012)
  16. Rao G.V., Annamalai T., Kavitha K. and Mukhopadhyay T., Chemical examination and biological studies on the seeds of Psoralea corylifolia Linn., Res. J. Chem. Sci.,2(1), 50-58 (2012)
  17. Tamilarasi T. and Ananthi T., Phytochemical analysis and antimicrobial activity of Mimosa pudica Linn., Res. J. Chem. Sci.,2(2), 72-74 (2012)