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Effect of Ipomea Carnea (JACQ) Leaf Extract on the Brain Tissue of Heteropneustes Fossilis

Author Affiliations

  • 1Zoology Department, M.C. College, (Gauhati University) Barpeta, Assam, INDIA

Int. Res. J. Environment Sci., Volume 4, Issue (4), Pages 22-25, April,22 (2015)


Ipomea carnea was found abundantly in lower Assam, was observed to be neurotoxic effect to animal specially central nervous system. In the present investigation ethanolic extract of ipomoea carnea exposed Indian cat –fish H. fossilis.Fishes were divided in to four groups-one control group and three experimental groups.(Af1,AF2,AF3,). Fish were exposed to 5mg/mlconcentration for 96 hours. Neurotoxic behavior was observed in the experimental groups such as behavioral response of movement, unconsciousness, loss of weight, reduced intake of food was observed as compared to control. Histopathological study showed damage of histological and cytological picture of brain. In AF2 group neurons cell exhibited marked histopathological alteration as normal cell converted to round, pear shaped and elongated structure.Occurrence of vacuolation around the nucleus and the nucleus shifted to the side of vacuoles were significant feature. In AF3 and AF4 group most of the nucleus to round large and vacuolar the number of nucleus were appear to be more than control. Which indicate meosis of cell. Finally they demyelization, necrosis in inner modullarly region, blood capillary dilation and swelling as well as hyalinization of the cell body, along with astrocytoma like alteration of histological structucture of the brain. All these finding indicated that Ipomea carnea is a potent neurotoxic agent; It can be used as biopesticide.Further investigation is suggested.


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