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Autophagy: Molecular Insight and Role in Plant Programmed Cell Death and Defense Mechanism.

Author Affiliations

  • 1School of Life Sciences, B. S. Abdur Rahman University, Vandalur, Chennai-600048 (TN), INDIA

Int. Res. J. Biological Sci., Volume 4, Issue (2), Pages 78-83, February,10 (2015)


Autophagy is an evolutionary conserved pathway of vacuolar degradation of cytoplasmic constituents. The characteristic feature of the pathway is double membrane bound autophagosome which transfer the damaged and excessive cell components to the lysosome or vacuoles for degradation and recycling. Autophagy allows the cell to survive under nutrient starvation and various biotic and abiotic stresses. The molecular mechanism of autophagy has been studied in yeast to mammals and also in plants. Many Experimental results suggested that the basic molecular mechanism and pathways are conserved in yeast, mammals and plants to a large extent. This review highlights basic molecular autophagy and its role in defense mechanism and programmed cell death in plants.


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