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Appraisal of in vitro Antioxidant prospective of Premna corymbosa

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Author Affiliations

  • 1Research and Development Centre, Bharathiar University, Coimbatore – 641 046, INDIA
  • 2PG and Research Department of Biochemistry, Rajah Serfoji Government College (A), Thanjavur – 613005, Tamilnadu, INDIA
  • 3Armats Bioproducts Unit, Armats Biotek Pvt Ltd., Guindy, Chennai 600 032, INDIA

Int. Res. J. Biological Sci., Volume 3, Issue (10), Pages 70-75, October,10 (2014)

Abstract

Medicinal plants grip decisive liability in enhancement of individual around planet. Hi-tech explorations of medicinal plants have been instigated in copious parts of our nation as of their hand-outs to health care. In numerous bedlam, the free radical intervened injure may play an indispensable role. Free radical speculation has drastically enthused nosiness in thwarting human ailments incorporating diabetes, atherosclerosis, stroke, and rheumatoid arthritis. Antioxidants can expire or hold up the oxidation procedure by scavenging free radicals. Considering the veracity, the contemporary exploration was predestined to appraise antioxidant prospective of methanol leaf extract from Premna corymbosa. Antioxidant bustle resoluted by in vitro ordeal comprising DPPH radical foraging, hydroxyl radical foraging activity, metal chelating ability and total antioxidant activity. From outcome, extract exemplified momentous antioxidant bustle with an IC50 of 58µg/ml in DPPH foraging and 865µg/ml in hydroxyl scavenging assays. IC50 of extort inmetalchelating and total antioxidant bustle established to be 623 µg/ml and 140g/ml. Results enunciated pledging antioxidant prospective of methanol leaf extort from Premna corymbosa.

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