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Methicillin-Resistant Staphylococcus Aureus: A Brief Review

Author Affiliations

  • 1Department of Microbiology, Gurunanak Institute of Dental Science and Research, Panihati, Kolkata-700114, West Bengal, INDIA
  • 2 Dept. of Pedodontics and Preventive Dentistry, Gurunanak Institute of Dental Science & Research, Panihati, Kolkata-700114, WB, INDIA

Int. Res. J. Biological Sci., Volume 1, Issue (7), Pages 65-71, November,10 (2012)

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium responsible for several difficult-to-treat infections in humans. It is also called multidrug-resistant Staphylococcus aureus and oxacillin-resistant Staphylococcus aureus (ORSA). MRSA is any strain of Staphylococcus aureus that has developed, through the process of natural selection, resistance to beta-lactam antibiotics, which include the penicillins (methicillin, dicloxacillin, nafcillin, oxacillin, etc.) and the cephalosporins. Strains unable to resist these antibiotics are classified as methicillin-sensitive Staphylococcus aureus, or MSSA. The evolution of such resistance does not cause the organism to be more intrinsically virulent than strains of Staphylococcus aureus that have no antibiotic resistance, but resistance does make MRSA infection more difficult to treat with standard types of antibiotics and thus more dangerous.MRSA is especially troublesome in hospitals, prisons and nursing homes, where patients with open wounds, invasive devices, and weakened immune systems are at greater risk of infection than the general public.

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