International E-publication: Publish Projects, Dissertation, Theses, Books, Souvenir, Conference Proceeding with ISBN.  International E-Bulletin: Information/News regarding: Academics and Research

Organophosphate Poisoning: A Retrospective Study of 50 Cases at J. L. N. Medical College, Ajmer, India

Author Affiliations

  • 1Department of Forensic Medicine, J.L.N. Medical College, Ajmer, India
  • 2Department of Forensic Medicine, J.L.N. Medical College, Ajmer, India

Res. J. Forensic Sci., Volume 4, Issue (5), Pages 1-5, May,29 (2016)

Abstract

Our Study was aimed to analyse the pattern, the other demographic factors of medicolegal significance along with clinical prognosis of organophosphorus poisoning in Central Rajasthan (Ajmer) region. 50 patients were included in our study who were admitted in the emergency ward and diagnosed and labelled as Organophosphate Poisoning in case sheet during the period of April 2015 to July 2015.Majority of cases were from rural background (66%), with the most cases belonging to age group 21 to 30 years (40%).The Mortality rate was 12%. Organophosphorus Poisoning has high incidence along with mortality in this region. The Organophosphorus compounds are easily approachable to general public. Today’s pattern of life leads to Organophosphorus compounds as a common poison to commit suicide. Accidental Exposure among the individuals handling and spraying insecticide in the field was common due to inadequate education and preventive measures.

References

  1. Reddy KSN (2010)., The Essentials of Forensic Medicine and Toxicology, 29th Edition. Hyderabad: K. Suguna Devi, 446
  2. Dash SK, Mohanty MK, Patnaik KK and Mohanty S. (2005)., The sociodemographic profile of the poisoning cases., J. Ind. Acad. Forensic med. 3, 133–38.
  3. Palaniappen V. (2015)., API textbook of medicine., 10th Edn. Jaypee bothers Medical publishers Pvt. Ltd. 427
  4. Eddleston M., Szinicz L., Eyer P. and Buckley N. (2002)., Oximes in acute organophosphorus pesticide poisoning: a systematic review of clinical trials., Q J Med. 95, 275-83.
  5. Worek F., Backer M. and Thierman H et. al. (1997)., Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning., Hum Exp Toxicol, 16, 466- 72.
  6. Worek F., Diepold C. and Eyer P. (1999)., Dimethylphosphoryl-inhibited human cholinesterases: inhibition, Reactivation and Ageing Kinetics., Arch Toxicol, 73, 7-14.
  7. Tripathi K.D. (1999)., Essentials of Medical Pharmacology., 4th ed. Jaypee Brothers. 89.
  8. Senanayake N. and Karalliedde L. (1987)., Neurotoxic effects of organophosphorus insecticides., An intermediate syndrome. N Engl J Med., 316, 761-63.
  9. John M., Oommen A., Zachariah A. (2003)., Muscle injury in Organophosphorus poisoning and its role in the development of Intermediate Syndrome., Neurotoxicology, 24, 43-53.
  10. Sahin H.A., Sahin I. and Arabaci F. (2003)., Sociodemographic factors in organ- ophosphorus poisoning: A prospective study., Hum. Exp. Toxicol., 22(7), 349–53.
  11. Siwach S.B. and Gupta A. (1995). 3The profile of acute poisoning in Haryana-a Rohtak study., JAPI, 43(11), 756–59., undefined
  12. Gupta B.D. and Vaghela P.C. (2005)., The profile of fatal poisoning in and around Jamnagar., J. Ind. Acad. Forensic Med. 27(3), 145-48.
  13. Mishra A., Shukla S.K., Yadav M.K. and Gupta A.K. (2012)., Epidemiological study of Medico-legal organophosphorus poisoning in central region of Nepal., J Forensic Res., 3, 167.doi:10.4172/2157-7145.1000167.
  14. Emerson G.M., Gray N.M., Jelinek G.A., Mountain D. and Mead H.J. (1999)., Organophosphate poisoning in Perth, Western Australia, 1987-1996., J. Emerg. Med., 17(2), 273–77.
  15. Dhaval J. Patel and Pawan R. Tekade (2011)., Profile of Organophosphorus Poisoning at Maharani Hospital, Jagdalpur, Chhattisgarh: A Three Years Study., J Indian Acad Forensic Med., 33(2), 102.
  16. Palimar V., Saralaya K.M., Arun M., Mohanty M.K. and Singh B. (2005)., The profile of methyl parathion poisoning in Manipal, India., J. Ind. Soc. Toxicol. 1(2), 35–37
  17. Sinha U.S., Kapoor A.K., Agnihotri A.K. and Srivastava P.C. (1999)., A profile of the poisoning cases which were admitted to the SRN Hospital, Allahabad, with a special reference to aluminium phosphide poisoning., J. Forensic Med. Toxicol. 16(1), 40–43.
  18. Karalliedde L. et. al. (1988)., Acute Organophosphorous poisoning in Sri Lanka, Forens Sci Inter, 36, 97-100.
  19. Banerjee I., Tripathi S.K. and Roy A.S. (2012)., Clinico- epidemiological characteristics of patients presenting with organophosphorus poisoning., North Am J Med Sci., 4, 147-50.
  20. Kora S.A., Doddamani G.B., Halagali G.R. and Vijayamahantesh S.N. (2011)., Boke Umakanth Sociodemographic Profile of the Organophosphorus poisoning Cases in southern India., Journal of clinical and diagnostic research, 5(5), 953-956.
  21. Karki P., Hansdak S.G. Bhandari S., Shukla A. and Koirala S.A. (2001)., A clinico- epidemiological study of organophosphorus poisoning at a rural bases teaching Hospital in eastern Nepal., Trop. Doct., 31(1), 32–34.
  22. Somasundaram K.V., Ashok Patil and Shukla S.K. (2009)., Epidemiological profile of OP poisoning cases treated at Pravara Hospital, Loni, India., Indian Journal of Prev. Soc. Med., 40(3-4).